Phosphodiesterase 4B mediates extracellular signal-regulated kinase-dependent up-regulation of mucin MUC5AC protein by Streptococcus pneumoniae by inhibiting cAMP-protein kinase A-dependent MKP-1 phosphatase pathway

Jiyun Lee, Kensei Komatsu, Byung Cheol Lee, Jae Hyang Lim, Hirofumi Jono, Haidong Xu, Hirofumi Kai, Z. John Zhang, Chen Yan, Jian Dong Li

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Biochemistry, Genetics and Molecular Biology

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Immunology and Microbiology