Peripheral T cell lymphoma in Asia

Sanghui Park, Young Hyeh Ko

Research output: Contribution to journalReview articlepeer-review

40 Scopus citations

Abstract

Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T- and NK-cell neoplasms, the incidence of which is higher in Asian countries than in Western countries. Although its etiology is mainly unknown, several risk factors (such as genetic factors, abnormal immunity, environmental factors, and infectious causes) have been proposed. PTCL are classified based on a combination of several parameters, including morphology, site of presentation, viral status, immunophenotype, and specific genetic alterations. Their classification is ongoing, with the emergence of new entities and refinement of existing entities because of the development of diagnostic markers and new genetic alterations. This review presents epidemiologic data for PTCL in Asia, together with recent progress in the pathology of PTCL compared with the WHO 2008 classification.

Original languageEnglish
Pages (from-to)227-239
Number of pages13
JournalInternational Journal of Hematology
Volume99
Issue number3
DOIs
StatePublished - Mar 2014

Keywords

  • Asia
  • Epidemiology
  • Malignant lymphoma
  • Pathology
  • T cell

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