TY - JOUR
T1 - Peripheral T cell lymphoma in Asia
AU - Park, Sanghui
AU - Ko, Young Hyeh
N1 - Funding Information:
Acknowledgments This study was supported by a Samsung Biomedical Research Institute Grant (No. SP1B20412).
PY - 2014/3
Y1 - 2014/3
N2 - Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T- and NK-cell neoplasms, the incidence of which is higher in Asian countries than in Western countries. Although its etiology is mainly unknown, several risk factors (such as genetic factors, abnormal immunity, environmental factors, and infectious causes) have been proposed. PTCL are classified based on a combination of several parameters, including morphology, site of presentation, viral status, immunophenotype, and specific genetic alterations. Their classification is ongoing, with the emergence of new entities and refinement of existing entities because of the development of diagnostic markers and new genetic alterations. This review presents epidemiologic data for PTCL in Asia, together with recent progress in the pathology of PTCL compared with the WHO 2008 classification.
AB - Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T- and NK-cell neoplasms, the incidence of which is higher in Asian countries than in Western countries. Although its etiology is mainly unknown, several risk factors (such as genetic factors, abnormal immunity, environmental factors, and infectious causes) have been proposed. PTCL are classified based on a combination of several parameters, including morphology, site of presentation, viral status, immunophenotype, and specific genetic alterations. Their classification is ongoing, with the emergence of new entities and refinement of existing entities because of the development of diagnostic markers and new genetic alterations. This review presents epidemiologic data for PTCL in Asia, together with recent progress in the pathology of PTCL compared with the WHO 2008 classification.
KW - Asia
KW - Epidemiology
KW - Malignant lymphoma
KW - Pathology
KW - T cell
UR - http://www.scopus.com/inward/record.url?scp=84899423259&partnerID=8YFLogxK
U2 - 10.1007/s12185-014-1520-3
DO - 10.1007/s12185-014-1520-3
M3 - Review article
C2 - 24481942
AN - SCOPUS:84899423259
SN - 0925-5710
VL - 99
SP - 227
EP - 239
JO - International Journal of Hematology
JF - International Journal of Hematology
IS - 3
ER -