TY - JOUR
T1 - Parental exposure to organic solvents and reduced birth weight
AU - Ha, Eunhee
AU - Cho, Sung Il
AU - Chen, Changzhong
AU - Smith, Thomas J.
AU - Xu, Xiping
AU - Christiani, David C.
AU - Chen, Dafang
AU - Ryan, Louise
N1 - Funding Information:
This study was supported in part by grants HD32505 from the National Institute of Child Health and Human Development; ES08337 and ES00002 from the National Institute of Environmental Health Science; OH03027 from the National Institute of Occupational Safety and Health; G73B1382 from the U.S. Environmental Protection Agency; and 20-FY98-0701 from the March of Dimes Birth Defects Foundation. Submitted for publication August 21, 2000; revised; accepted for publication April 2, 2001. Requests for reprints should be sent to Eunhee Ha, M.D., Ph.D., Department of Preventive Medicine, Ewha Woman’s University College of Medicine, 911 -1 Mok-&Dong Yangchun-Gu, Seoul, South Korea. E-mail: eunheehaQmm.ewha.ac.kr
PY - 2002
Y1 - 2002
N2 - The authors investigated the association of birth weight with maternal and paternal exposure to organic solvents in 1,222 couples employed in a large petrochemical corporation in Beijing, China, during the period between 1994 and 1998. A trained interviewer assessed parental exposures to organic solvents. The authors used generalized additive models to examine the association between birth weight and parental exposure to organic solvents. After the authors adjusted for potential confounders, maternal exposure to solvents was significantly associated with reduced birth weight (-81.7 gm, 95% confidence interval = −106.3, −3.1), and reduced birth weights of female babies and of younger mothers' babies were statistically significant. Maternal exposure to organic solvents was associated with reduced birth weight in this population, but paternal exposure to organic solvents was not similarly associated.
AB - The authors investigated the association of birth weight with maternal and paternal exposure to organic solvents in 1,222 couples employed in a large petrochemical corporation in Beijing, China, during the period between 1994 and 1998. A trained interviewer assessed parental exposures to organic solvents. The authors used generalized additive models to examine the association between birth weight and parental exposure to organic solvents. After the authors adjusted for potential confounders, maternal exposure to solvents was significantly associated with reduced birth weight (-81.7 gm, 95% confidence interval = −106.3, −3.1), and reduced birth weights of female babies and of younger mothers' babies were statistically significant. Maternal exposure to organic solvents was associated with reduced birth weight in this population, but paternal exposure to organic solvents was not similarly associated.
KW - Organic solvents
KW - Parental exposure
KW - Reduced birth weight
UR - http://www.scopus.com/inward/record.url?scp=0036558483&partnerID=8YFLogxK
U2 - 10.1080/00039890209602938
DO - 10.1080/00039890209602938
M3 - Article
C2 - 12510663
AN - SCOPUS:0036558483
SN - 0003-9896
VL - 57
SP - 207
EP - 214
JO - Archives of Environmental Health
JF - Archives of Environmental Health
IS - 3
ER -
