Overexpression, crystallization and preliminary X-ray crystallographic analysis of hypothetical protein SAV0479 from Staphylococcus aureus Mu50

Chinar Pathak, Sun Bok Jang, Hookang Im, Hye Jin Yoon, Bong Jin Lee

Research output: Contribution to journalArticlepeer-review

Abstract

SAV0479, a hypothetical protein from the Mu50 strain of methicillin- and vancomycin-resistant Staphylococcus aureus, was selected for structure and function determination as part of a structural genomics project. Here, the cloning, overexpression, purification and crystallization of SAV0479 are reported. Crystals were obtained by the hanging-drop vapour-diffusion method and diffraction data were collected to a resolution of 2.8 Å. The crystals belonged to space group P3121, with unit-cell parameters a = b = 81.48, c = 82.53 Å. Three monomers of SAV0479 are present in each asymmetric unit.

Original languageEnglish
Pages (from-to)405-407
Number of pages3
JournalActa Crystallographica Section F: Structural Biology and Crystallization Communications
Volume69
Issue number4
DOIs
StatePublished - Apr 2013

Keywords

  • hypothetical protein SAV0479
  • methicillin- and vancomycin-resistant Staphylococcus aureus

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