Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities

Ah Ram Chang, Kyubo Kim, Hak Jae Kim, Il Han Kim, Charn Il Park, Yoon Kyung Jun

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.

Original languageEnglish
Pages (from-to)1233-1239
Number of pages7
JournalInternational Journal of Radiation Oncology Biology Physics
Volume65
Issue number4
DOIs
StatePublished - 15 Jul 2006

Keywords

  • Kimura's disease
  • Radiotherapy
  • Systemic steroids

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