Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities

Ah Ram Chang; Kyubo Kim; Hak Jae Kim; Il Han Kim; Charn Il Park; Yoon Kyung Jun

doi:10.1016/j.ijrobp.2006.02.024

Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities

Ah Ram Chang, Kyubo Kim, Hak Jae Kim, Il Han Kim, Charn Il Park, Yoon Kyung Jun

Department of Radiation Oncology

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.

Original language	English
Pages (from-to)	1233-1239
Number of pages	7
Journal	International Journal of Radiation Oncology Biology Physics
Volume	65
Issue number	4
DOIs	https://doi.org/10.1016/j.ijrobp.2006.02.024
State	Published - 15 Jul 2006

Keywords

Kimura's disease
Radiotherapy
Systemic steroids

Access to Document

10.1016/j.ijrobp.2006.02.024

Cite this

@article{d22a4f28278649e494e08a91317b8377,

title = "Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities",

abstract = "Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.",

keywords = "Kimura's disease, Radiotherapy, Systemic steroids",

author = "Chang, {Ah Ram} and Kyubo Kim and Kim, {Hak Jae} and Kim, {Il Han} and Park, {Charn Il} and Jun, {Yoon Kyung}",

year = "2006",

month = jul,

day = "15",

doi = "10.1016/j.ijrobp.2006.02.024",

language = "English",

volume = "65",

pages = "1233--1239",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

number = "4",

}

TY - JOUR

T1 - Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities

AU - Chang, Ah Ram

AU - Kim, Kyubo

AU - Kim, Hak Jae

AU - Kim, Il Han

AU - Park, Charn Il

AU - Jun, Yoon Kyung

PY - 2006/7/15

Y1 - 2006/7/15

N2 - Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.

AB - Purpose: To evaluate the clinical outcome of Kimura's disease and to identify the optimal treatment regimen for Kimura's disease. Methods and Materials: Between 1984 and 2003, 14 patients with Kimura's disease were treated with radiotherapy (RT) and 9 patients were treated with local excision or systemic steroids. The radiation doses ranged from 20 to 45 Gy. Immunohistochemical studies were performed in 13 cases. Results: At RT completion, a marked response in terms of tumor size was noted in most cases. The median follow-up was 65 months. Local control was obtained in 9 (64.3%) of the 14 in the RT group and in 2 (22.2%) of the 9 in the non-RT group. No secondary malignancies were observed in the RT group. Conclusion: These results supports the finding that RT is more effective against Kimura's disease. Simple or immunohistochemical features did not influence the treatment outcome.

KW - Kimura's disease

KW - Radiotherapy

KW - Systemic steroids

UR - http://www.scopus.com/inward/record.url?scp=33745225186&partnerID=8YFLogxK

U2 - 10.1016/j.ijrobp.2006.02.024

DO - 10.1016/j.ijrobp.2006.02.024

M3 - Article

C2 - 16750313

AN - SCOPUS:33745225186

SN - 0360-3016

VL - 65

SP - 1233

EP - 1239

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

IS - 4

ER -

Outcomes of Kimura's disease after radiotherapy or nonradiotherapeutic treatment modalities

Abstract

Keywords

Access to Document

Fingerprint

Cite this