Osteonecrosis of the Femoral Head: an Updated Review of ARCO on Pathogenesis, Staging and Treatment

Jeremy T. Hines, Woo Lam Jo, Quanjun Cui, Michael A. Mont, Kyung Hoi Koo, Edward Y. Cheng, Stuart B. Goodman, Yong Chan Ha, Phillippe Hernigou, Lynne C. Jones, Shin Yoon Kim, Takashi Sakai, Nobuhiko Sugano, Takuaki Yamamoto, Mel S. Lee, Dewei Zhao, Wolf Drescher, Tae Young Kim, Young Kyun Lee, Byung Ho YoonSeung Hoon Baek, Wataru Ando, Hong Seok Kim, Jung Wee Park

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Non-traumatic osteonecrosis of the femoral head (ONFH) usually affects adults younger than 50 years and frequently leads to femoral head collapse and subsequent arthritis of the hip. It is becoming more prevalent along with increasing use of corticosteroids for the adjuvant therapy of leukemia and other myelogenous diseases as well as management of organ transplantation. This review updated knowledge on the pathogenesis, classification criteria, staging system, and treatment of ONFH.

Original languageEnglish
Article numbere177
Pages (from-to)1-15
Number of pages15
JournalJournal of Korean Medical Science
Issue number24
StatePublished - 2021

Bibliographical note

Publisher Copyright:
© 2021 The Korean Academy of Medical Sciences. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


  • Avascular Necrosis
  • Femoral Head
  • Hip
  • Osteonecrosis


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