(Chemical Equation Presented) ARC de triomphe: Ortho-TMS benzaldehyde permits efficient multicomponent union of a variety of nucleophiles and electrophiles, including the first example of a Pd-mediated ARC Type II process. A "proof-of-concept" synthetic sequence was designed and implemented for construction of a focused library of "natural product-like" compounds (see scheme). ARC: anion relay chemistry.
|Number of pages||5|
|Journal||Angewandte Chemie - International Edition|
|State||Published - 1 Sep 2008|
- Anion relay chemistry
- Molecular diversity
- Natural products