Optimization of recombinant Escherichia coli fed-batch fermentation for bovine somatotropin

Sung Kwan Yoon; Seon Hun Kwon; Myoung Gyu Park; Whan Koo Kang; Tai Hyun Park

doi:10.1007/BF01020836

Optimization of recombinant Escherichia coli fed-batch fermentation for bovine somatotropin

Sung Kwan Yoon, Seon Hun Kwon, Myoung Gyu Park, Whan Koo Kang, Tai Hyun Park

Department of Nutritional Science & Food Management

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Optimum specific growth rate for the production of recombinant bovine somatotropin (bST) was investigated in fed-batch E. coli fermentation with a controlled specific growth rate. Maximum specific bST concentration based on cell mass decreases linearly with the controlled specific growth rate. Productivity of bST is expressed by a quadratic equation as a function of the specific growth rate and has a maximum value at μ=0.23 hr^-1.

Original language	English
Pages (from-to)	1119-1124
Number of pages	6
Journal	Biotechnology Letters
Volume	16
Issue number	11
DOIs	https://doi.org/10.1007/BF01020836
State	Published - Nov 1994

Access to Document

10.1007/BF01020836

Cite this

@article{090716f121494b029b5e212ed1c2c057,

title = "Optimization of recombinant Escherichia coli fed-batch fermentation for bovine somatotropin",

abstract = "Optimum specific growth rate for the production of recombinant bovine somatotropin (bST) was investigated in fed-batch E. coli fermentation with a controlled specific growth rate. Maximum specific bST concentration based on cell mass decreases linearly with the controlled specific growth rate. Productivity of bST is expressed by a quadratic equation as a function of the specific growth rate and has a maximum value at μ=0.23 hr-1.",

author = "Yoon, {Sung Kwan} and Kwon, {Seon Hun} and Park, {Myoung Gyu} and Kang, {Whan Koo} and Park, {Tai Hyun}",

year = "1994",

month = nov,

doi = "10.1007/BF01020836",

language = "English",

volume = "16",

pages = "1119--1124",

journal = "Biotechnology Letters",

issn = "0141-5492",

publisher = "Springer Netherlands",

number = "11",

}

TY - JOUR

T1 - Optimization of recombinant Escherichia coli fed-batch fermentation for bovine somatotropin

AU - Yoon, Sung Kwan

AU - Kwon, Seon Hun

AU - Park, Myoung Gyu

AU - Kang, Whan Koo

AU - Park, Tai Hyun

PY - 1994/11

Y1 - 1994/11

N2 - Optimum specific growth rate for the production of recombinant bovine somatotropin (bST) was investigated in fed-batch E. coli fermentation with a controlled specific growth rate. Maximum specific bST concentration based on cell mass decreases linearly with the controlled specific growth rate. Productivity of bST is expressed by a quadratic equation as a function of the specific growth rate and has a maximum value at μ=0.23 hr-1.

AB - Optimum specific growth rate for the production of recombinant bovine somatotropin (bST) was investigated in fed-batch E. coli fermentation with a controlled specific growth rate. Maximum specific bST concentration based on cell mass decreases linearly with the controlled specific growth rate. Productivity of bST is expressed by a quadratic equation as a function of the specific growth rate and has a maximum value at μ=0.23 hr-1.

UR - http://www.scopus.com/inward/record.url?scp=0028081211&partnerID=8YFLogxK

U2 - 10.1007/BF01020836

DO - 10.1007/BF01020836

M3 - Article

AN - SCOPUS:0028081211

SN - 0141-5492

VL - 16

SP - 1119

EP - 1124

JO - Biotechnology Letters

JF - Biotechnology Letters

IS - 11

ER -

Optimization of recombinant Escherichia coli fed-batch fermentation for bovine somatotropin

Abstract

Access to Document

Fingerprint

Cite this