Abstract
One-pot three-component reactions using copper(i) acetylide, azide, allyl iodide, and NaOH have been developed. The reactions proceed smoothly at room temperature to afford 5-allyl-1,2,3-triazoles, which can be further transformed into a variety of 1,2,3-triazole-fused bi-/tricyclic scaffolds. This method offers the most efficient, convenient, and practical route towards useful polycyclic scaffolds in moderate to excellent yields.
| Original language | English |
|---|---|
| Pages (from-to) | 2759-2767 |
| Number of pages | 9 |
| Journal | RSC Advances |
| Volume | 8 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2018 |
Bibliographical note
Publisher Copyright:© The Royal Society of Chemistry 2018.