Novel 1,4-diphosphanes with imidazolidin-2-one Backbones as chiral ligands: Highly enantioselective Rh-catalyzed hydrogenation of enamides

Sang Gi Lee, Yong Jian Zhang, Choong Eui Song, Jae Kyun Lee, Jung Hoon Choi

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

Appropriate gauche steric interactions between the N-substituents and the phosphanylmethyl groups (see picture, top right) in the novel 1,4-diphosphane ligands 1 having an imidazolidin-2-one backbone affect the conformational flexibility of the seven-membered chelate ring formed by coordination to a metal atom. Thus, Rh complexes of 1 are excellent catalysts for enantioselective hydrogenation of enamides (bottom, cod= cyclooacta-1,5-diene).

Original languageEnglish
Pages (from-to)847-849
Number of pages3
JournalAngewandte Chemie - International Edition
Volume41
Issue number5
DOIs
StatePublished - 1 Mar 2002

Keywords

  • Asymmetric catalysis
  • Hydrogenation
  • P ligands
  • Rhodium

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