Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B

Medicine & Life Sciences

• Haemophilus influenzae 100%
• NF-kappa B 93%
• Cyclooxygenase 2 92%
• p38 Mitogen-Activated Protein Kinases 90%
• Dinoprostone 85%
• Epithelial Cells 62%
• Lung 47%
• Cyclooxygenase 1 28%
• Alveolar Epithelial Cells 16%
• A549 Cells 16%
• Messenger RNA 12%
• DNA 12%
• Pneumonia 11%
• Haemophilus Infections 10%
• Phosphorylation 10%
• In Vitro Techniques 9%
• Toll-Like Receptor 2 9%
• Cyclooxygenase Inhibitors 8%
• Cyclooxygenase 2 Inhibitors 8%
• Electrophoretic Mobility Shift Assay 8%
• HEK293 Cells 7%
• Gram-Negative Bacteria 7%
• Bacterial Infections 6%
• Knockout Mice 6%
• Chronic Obstructive Pulmonary Disease 6%
• Reverse Transcription 6%
• Anti-Inflammatory Agents 5%
• Enzyme-Linked Immunosorbent Assay 5%
• Western Blotting 4%
• Polymerase Chain Reaction 4%
• Proteins 2%
• Therapeutics 1%