Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction

Jinkwon Kim; Tae Jin Song; Dongbeom Song; Hye Sun Lee; Chung Mo Nam; Hyo Suk Nam; Young Dae Kim; Ji Hoe Heo

doi:10.1161/STROKEAHA.113.001111

Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction

Jinkwon Kim, Tae Jin Song, Dongbeom Song, Hye Sun Lee, Chung Mo Nam, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo

Department of Neurology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

BACKGROUND AND PURPOSE - : We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke. METHODS - : We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI. RESULTS - : NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes. CONCLUSIONS - : The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.

Original language	English
Pages (from-to)	2013-2015
Number of pages	3
Journal	Stroke
Volume	44
Issue number	7
DOIs	https://doi.org/10.1161/STROKEAHA.113.001111
State	Published - Jul 2013

Keywords

acute stroke
angiography
atherosclerosis
prognosis

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10.1161/STROKEAHA.113.001111

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title = "Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction",

abstract = "BACKGROUND AND PURPOSE - : We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke. METHODS - : We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI. RESULTS - : NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes. CONCLUSIONS - : The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.",

keywords = "acute stroke, angiography, atherosclerosis, prognosis",

author = "Jinkwon Kim and Song, {Tae Jin} and Dongbeom Song and Lee, {Hye Sun} and Nam, {Chung Mo} and Nam, {Hyo Suk} and Kim, {Young Dae} and Heo, {Ji Hoe}",

year = "2013",

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doi = "10.1161/STROKEAHA.113.001111",

language = "English",

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number = "7",

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T1 - Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction

AU - Kim, Jinkwon

AU - Song, Tae Jin

AU - Song, Dongbeom

AU - Lee, Hye Sun

AU - Nam, Chung Mo

AU - Nam, Hyo Suk

AU - Kim, Young Dae

AU - Heo, Ji Hoe

PY - 2013/7

Y1 - 2013/7

N2 - BACKGROUND AND PURPOSE - : We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke. METHODS - : We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI. RESULTS - : NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes. CONCLUSIONS - : The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.

AB - BACKGROUND AND PURPOSE - : We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke. METHODS - : We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI. RESULTS - : NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes. CONCLUSIONS - : The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.

KW - acute stroke

KW - angiography

KW - atherosclerosis

KW - prognosis

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SP - 2013

EP - 2015

JO - Stroke

JF - Stroke

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ER -

Nonrelevant cerebral atherosclerosis is a strong prognostic factor in acute cerebral infarction

Abstract

Keywords

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