Abstract
Chemical investigation of a marine-derived actinomycete isolated from marine sediments collected off the coast of southern California and identified as a Nocardiopsis sp. (strain CNQ115) led to the isolation of two new 4-aminoimidazole alkaloids, nocarimidazoles A (1) and B (2). The chemical structures of nocarimidazoles A and B were assigned by interpretation of NMR spectroscopic data and through methylation to yield monomethyl and dimethyl derivatives. Nocarimidazoles A and B possess a 4-aminoimidazole ring combined with a conjugated carbonyl side chain, which is rarely found in microbial secondary metabolites.
| Original language | English |
|---|---|
| Pages (from-to) | 2846-2849 |
| Number of pages | 4 |
| Journal | Journal of Natural Products |
| Volume | 78 |
| Issue number | 11 |
| DOIs | |
| State | Published - 25 Nov 2015 |
Bibliographical note
Publisher Copyright:© 2015 The American Chemical Society and American Society of Pharmacognosy.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 14 Life Below Water
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