New RNA purine building blocks, 4'-selenopurine nucleosides: First synthesis and unusual mixture of sugar puckerings

Jinha Yu; Jin Hee Kim; Hyuk Woo Lee; Varughese Alexander; Hee Chul Ahn; Won Jun Choi; Jungwon Choi; Lak Shin Jeong

doi:10.1002/chem.201300741

New RNA purine building blocks, 4'-selenopurine nucleosides: First synthesis and unusual mixture of sugar puckerings

Jinha Yu
, Jin Hee Kim
, Hyuk Woo Lee
, Varughese Alexander
, Hee Chul Ahn
, Won Jun Choi
, Jungwon Choi
, Lak Shin Jeong

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Writer's blocks: The first synthesis of RNA purine building blocks, 4'-selenoadenosine and 4'-selenoguanosine was achieved from D-ribose by regioisomeric rearrangement, which was confirmed by X-ray crystallography. 4'-Selenoadenosine exists in an unusual mixture of north and south conformers in the solid state.

Original language	English
Pages (from-to)	5528-5532
Number of pages	5
Journal	Chemistry - A European Journal
Volume	19
Issue number	18
DOIs	https://doi.org/10.1002/chem.201300741
State	Published - 26 Apr 2013

Keywords

RNA
X-ray crystallography
nucleic acids
nucleosides
selenonucleosides

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10.1002/chem.201300741

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abstract = "Writer's blocks: The first synthesis of RNA purine building blocks, 4'-selenoadenosine and 4'-selenoguanosine was achieved from D-ribose by regioisomeric rearrangement, which was confirmed by X-ray crystallography. 4'-Selenoadenosine exists in an unusual mixture of north and south conformers in the solid state.",

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author = "Jinha Yu and Kim, \{Jin Hee\} and Lee, \{Hyuk Woo\} and Varughese Alexander and Ahn, \{Hee Chul\} and Choi, \{Won Jun\} and Jungwon Choi and Jeong, \{Lak Shin\}",

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AU - Yu, Jinha

AU - Kim, Jin Hee

AU - Lee, Hyuk Woo

AU - Alexander, Varughese

AU - Ahn, Hee Chul

AU - Choi, Won Jun

AU - Choi, Jungwon

AU - Jeong, Lak Shin

PY - 2013/4/26

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AB - Writer's blocks: The first synthesis of RNA purine building blocks, 4'-selenoadenosine and 4'-selenoguanosine was achieved from D-ribose by regioisomeric rearrangement, which was confirmed by X-ray crystallography. 4'-Selenoadenosine exists in an unusual mixture of north and south conformers in the solid state.

KW - RNA

KW - X-ray crystallography

KW - nucleic acids

KW - nucleosides

KW - selenonucleosides

UR - https://www.scopus.com/pages/publications/84876892147

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DO - 10.1002/chem.201300741

M3 - Article

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JF - Chemistry - A European Journal

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ER -

New RNA purine building blocks, 4'-selenopurine nucleosides: First synthesis and unusual mixture of sugar puckerings

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Keywords

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