New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+

Han Na Lee, Ha Na Kim, K. M.K. Swamy, Min Sun Park, Jimi Kim, Hyunsook Lee, Keun Hyeung Lee, Sungsu Park, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg2+ and Cd2+ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg2+ or Cd2+ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg2+ and Cd2+ ions in mammalian cells.

Original languageEnglish
Pages (from-to)1261-1265
Number of pages5
JournalTetrahedron Letters
Volume49
Issue number7
DOIs
StatePublished - 11 Feb 2008

Fingerprint

Dive into the research topics of 'New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+'. Together they form a unique fingerprint.

Cite this