New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+

Han Na Lee; Ha Na Kim; K. M.K. Swamy; Min Sun Park; Jimi Kim; Hyunsook Lee; Keun Hyeung Lee; Sungsu Park; Juyoung Yoon

doi:10.1016/j.tetlet.2007.11.158

New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg²⁺ and Cd²⁺

Han Na Lee, Ha Na Kim, K. M.K. Swamy, Min Sun Park, Jimi Kim, Hyunsook Lee, Keun Hyeung Lee, Sungsu Park, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg²⁺ and Cd²⁺ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg²⁺ or Cd²⁺ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg²⁺ and Cd²⁺ ions in mammalian cells.

Original language	English
Pages (from-to)	1261-1265
Number of pages	5
Journal	Tetrahedron Letters
Volume	49
Issue number	7
DOIs	https://doi.org/10.1016/j.tetlet.2007.11.158
State	Published - 11 Feb 2008

Bibliographical note

Funding Information:
This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), Korea Ministry of Environment as ‘The Eco-technopia 21 project’ and BK21.

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10.1016/j.tetlet.2007.11.158

Cite this

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title = "New acridine derivatives bearing immobilized azacrown or azathiacrown ligand as fluorescent chemosensors for Hg2+ and Cd2+",

abstract = "Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg2+ and Cd2+ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg2+ or Cd2+ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg2+ and Cd2+ ions in mammalian cells.",

author = "Lee, {Han Na} and Kim, {Ha Na} and Swamy, {K. M.K.} and Park, {Min Sun} and Jimi Kim and Hyunsook Lee and Lee, {Keun Hyeung} and Sungsu Park and Juyoung Yoon",

note = "Funding Information: This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), Korea Ministry of Environment as {\textquoteleft}The Eco-technopia 21 project{\textquoteright} and BK21. ",

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AU - Lee, Han Na

AU - Kim, Ha Na

AU - Swamy, K. M.K.

AU - Park, Min Sun

AU - Kim, Jimi

AU - Lee, Hyunsook

AU - Lee, Keun Hyeung

AU - Park, Sungsu

AU - Yoon, Juyoung

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PY - 2008/2/11

Y1 - 2008/2/11

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