Abstract
Two new acridine derivatives bearing azacrown or azathiacrown ligand were synthesized as fluorescent chemosensors for Hg2+ and Cd2+ in aqueous solution. Compounds 1 and 2 displayed selective CHEF (chelation enhanced fluorescence) effects with Hg2+ or Cd2+ among the metal ions examined. The practical use of these probes was demonstrated by their applications to the detection of Hg2+ and Cd2+ ions in mammalian cells.
Original language | English |
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Pages (from-to) | 1261-1265 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 7 |
DOIs | |
State | Published - 11 Feb 2008 |
Bibliographical note
Funding Information:This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant (NRL) funded by the Korean government (MOST) (R04-2007-000-2007-0), Korea Ministry of Environment as ‘The Eco-technopia 21 project’ and BK21.