Neural activity modulation via ultrasound stimulation measured on multi-channel electrodes

Hee Sok Han, Seo Young Hwang, Faraz Akram, Hyun Jae Jeon, Sang Beom Nam, Sang Beom Jun, Jeong Tai Kim, Tae Seong Kim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Scopus citations


Recently ultrasound stimulation of the brain is getting a major attention as an external means of safe and effective brain stimulation to treat neurological diseases. Although it is known that ultrasound affects neural activities in the brain, the fundamental principles of ultrasound stimulation are not clearly elucidated yet. In this study, as an initial attempt to investigate the mechanism of neural activity modulation by ultrasound, we studied the changes in action potentials of cultured hippocampal neurons of rats using multi-electrode arrays. From our results, it was observed that ultrasound stimulation increases the frequencies of action potentials (i.e., the number of spikes), supporting the direct facilitation of neural activities by ultrasound.

Original languageEnglish
Title of host publicationWorld Congress on Engineering, WCE 2014
PublisherNewswood Limited
Number of pages4
ISBN (Print)9789881925275
StatePublished - 2014
EventWorld Congress on Engineering, WCE 2014 - London, United Kingdom
Duration: 2 Jul 20144 Jul 2014

Publication series

NameLecture Notes in Engineering and Computer Science
ISSN (Print)2078-0958


ConferenceWorld Congress on Engineering, WCE 2014
Country/TerritoryUnited Kingdom


  • Hippocampal neurons
  • Multi-electrode arrays
  • Neural activity modulation
  • Spike activities
  • Ultrasound brain stimulation


Dive into the research topics of 'Neural activity modulation via ultrasound stimulation measured on multi-channel electrodes'. Together they form a unique fingerprint.

Cite this