Recently, the necessity of using low-dose CT imaging with reduced noise has come to the forefront due to the risks involved in radiation. In order to acquire a high-resolution image from a low-resolution image which produces a relatively small amount of radiation, various algorithms including deep learning-based methods have been proposed. However, the current techniques have shown limited performance, especially with regard to losing fine details and blurring high-frequency edges. To enhance the previously suggested 2D patch-based denoising model, we have suggested the 3D block-based REDCNN model, employing convolution layers paired with deconvolution layers, shortcuts, and residual mappings. This process allows us to preserve the image structure and diagnostic features of an image, increasing image resolution by smoothing noise. Finally, we applied a bilateral filter in 3D and utilized a 2D-based Landweber iteration method to reduce remaining noise under a certain amplitude and prevent the edges from blurring. As a result, our proposed method effectively reduced Poisson noise level without losing diagnostic features and showed high performance in both qualitative and quantitative evaluation methods compared to ResNet2D, ResNet3D, REDCNN2D, and REDCNN3D.
|Title of host publication||Medical Imaging 2019|
|Subtitle of host publication||Physics of Medical Imaging|
|Editors||Taly Gilat Schmidt, Guang-Hong Chen, Hilde Bosmans|
|State||Published - 2019|
|Event||Medical Imaging 2019: Physics of Medical Imaging - San Diego, United States|
Duration: 17 Feb 2019 → 20 Feb 2019
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Conference||Medical Imaging 2019: Physics of Medical Imaging|
|Period||17/02/19 → 20/02/19|
Bibliographical noteFunding Information:
This research was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government, MSIP (grant no: NRF-2015M3A9A7029725 and NRF-2017M2A2A6A02070522, URL: http://nrf.re.kr). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. This work was never submitted, published, or presented before.
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- Bilateral filtering
- C-arm cone-beam CT
- Deep neural networks
- Imaging of lower extremities
- Landweber type iteration
- Medical image processing
- Noise reduction