Acid catalysed multi-electron reduction of nitrobenzene derivatives by an acid-stable NADH analogue, 10-methyl-9,10-dihydroacridine, occurs efficiently under mild conditions in the presence of perchloric acid in acetonitrile. Observation of CIDNP spectra as well as detailed kinetic studies on the acid catalysed reduction of nitrobenzene derivatives by AcrH2 and on the acid catalysed electron transfer from the excited state of [Ru(bpy)3]2+ to nitrobenzene derivatives has revealed that the multi-electron reduction of nitrobenzene derivatives by AcrH2 proceeds via acid catalysed electron transfer radical-chain reactions in which hydrogen transfer from AcrH2 to radicals produced by the acid catalysed one-electron reduction of nitrobenzene derivatives is the rate determining propagation step.
|Number of pages||6|
|Journal||Journal of the Chemical Society. Perkin Transactions 2|
|State||Published - 1991|