@inproceedings{62df9c36929d43dbbb8bd78ca18d3be0,
title = "Monitoring of amyloid kinetic growth by nanoplasmonic optics",
abstract = "The kinetic process of amyloid ! (A!42) fibrillation, critical event evoking Alzheimer disease, is investigated by a label-free biophotonic method. Utilizing gold nanoplasmonic particles (GNPs) as local light sources, the dynamic process of A! fibrillation was monitored by tracking random movement of GNPs. As fibrillation progressed, the movement was more restrictedly due to the growth of neighbor A! 42. Since GNPs do not have photo-bleaching and they can be used as optical antennas in living cells, this approach overcomes the limitation of current methods and broaden the quantitative analysis to probe in-situ and in-vivo monitoring of cellular kinetic events.",
keywords = "Amyloid ! (A!42) fibrillation, Gold nanoplasmonic particle (GNP), Lable-free, Particle tracking",
author = "Lee, {Sung S.} and Lee, {Luke P.}",
year = "2009",
language = "English",
isbn = "9780979806421",
series = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "881--883",
booktitle = "Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
note = "13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 ; Conference date: 01-11-2009 Through 05-11-2009",
}