Molecular nanoelectronics for label free DNA analysis

L. P. Lee, S. Oh, Y. Choi, J. S. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

An ultrasensitive nanogap junction is developed for label-free biomolecular detection. The nanogap junction can minimize the effects of electrode polarization. Without any label, dielectric detection of DNA hybridization is accomplished: the 70% and 12% changes of capacitance after hybridization were accomplished at 100 Hz for 10 μM and 10 fM concentrations of target DNA, respectively. The nanogap junction-based dielectric DNA detection method and the batch fabrication method of nanogap junctions might able to change the paradigm of functional genomics and proteomics.

Original languageEnglish
Title of host publication2002 International Microprocesses and Nanotechnology Conference, MNC 2002
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages286-287
Number of pages2
ISBN (Electronic)4891140313, 9784891140311
DOIs
StatePublished - 2002
EventInternational Microprocesses and Nanotechnology Conference, MNC 2002 - Tokyo, Japan
Duration: 6 Nov 20028 Nov 2002

Publication series

Name2002 International Microprocesses and Nanotechnology Conference, MNC 2002

Conference

ConferenceInternational Microprocesses and Nanotechnology Conference, MNC 2002
Country/TerritoryJapan
CityTokyo
Period6/11/028/11/02

Bibliographical note

Publisher Copyright:
© 2002 IEEE.

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