Among 312 rotavirus-positive samples collected from eight hospitals across South Korea during 2008 and 2009, the most prevalent circulating G genotype was G1 (35.9%), followed by G3 (24.7%), G2 (17.0%), G4 (7.7%), and G9 (2.6%). Notably, one unusual G11 lineage III strain-the first hypoendemic infection case in the world-was found. Of the P genotypes, P (43.9%) was the most common, followed by P (29.5%), P (9.3%) and P (0.6%). Determining G- and P-type combinations showed that G1P was the most prevalent (20.5%), followed by G2P (12.8%) and G3P (12.8%). These findings provide new information concerning the current prevalence and spread of the rare G11 rotavirus.