Abstract
Mohangamides A and B (1-2) were discovered from a marine Streptomyces sp. collected in an intertidal mud flat. The structures of the compounds were elucidated as novel dilactone-tethered pseudodimeric peptides bearing two unusual acyl chains and 14 amino acid residues based on comprehensive spectroscopic analysis. The absolute configurations of the mohangamides were determined by chemical derivatizations, followed by chromatographic and spectroscopic analyses. Mohangamide A displayed strong inhibitory activity against Candida albicans isocitrate lyase.
| Original language | English |
|---|---|
| Pages (from-to) | 712-715 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 17 |
| Issue number | 3 |
| DOIs | |
| State | Published - 6 Feb 2015 |
Bibliographical note
Publisher Copyright:© 2015 American Chemical Society.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 14 Life Below Water
Fingerprint
Dive into the research topics of 'Mohangamides A and B, new dilactone-tethered pseudo-dimeric peptides inhibiting candida albicans isocitrate lyase'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver