Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

Mi Kyung Kim; Kidong Kim; Jae Yong Han; Jeong Mook Lim; Yong Sang Song

doi:10.1007/s12263-011-0209-y

Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

Mi Kyung Kim, Kidong Kim, Jae Yong Han, Jeong Mook Lim, Yong Sang Song

Research output: Contribution to journal › Review article › peer-review

55 Scopus citations

Abstract

Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-κB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.

Original language	English
Pages (from-to)	109-115
Number of pages	7
Journal	Genes and Nutrition
Volume	6
Issue number	2
DOIs	https://doi.org/10.1007/s12263-011-0209-y
State	Published - May 2011

Keywords

Anti-inflammation
Chemoprevention
Ovarian cancer
Phytochemicals

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s12263-011-0209-y

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title = "Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer",

abstract = "Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-κB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.",

keywords = "Anti-inflammation, Chemoprevention, Ovarian cancer, Phytochemicals",

author = "Kim, \{Mi Kyung\} and Kidong Kim and Han, \{Jae Yong\} and Lim, \{Jeong Mook\} and Song, \{Yong Sang\}",

year = "2011",

month = may,

doi = "10.1007/s12263-011-0209-y",

language = "English",

volume = "6",

pages = "109--115",

journal = "Genes and Nutrition",

issn = "1555-8932",

publisher = "BioMed Central Ltd.",

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TY - JOUR

T1 - Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

AU - Kim, Mi Kyung

AU - Kim, Kidong

AU - Han, Jae Yong

AU - Lim, Jeong Mook

AU - Song, Yong Sang

PY - 2011/5

Y1 - 2011/5

N2 - Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-κB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.

AB - Inflammation has been suggested to be involved in cancer development and progression. Many clinical and experimental studies have shown that inflammation could contribute to ovarian carcinogenesis through activation of the NF-κB and AP-1 pathways by chronic inflammatory mediators. Phytochemicals, which are natural compounds derived from fruits and vegetables, have shown anti-inflammatory and anti-cancer effects. Due to their relatively low toxicity and easy accessibility, phytochemicals have been investigated for their chemopreventive potential against various cancers. In this review, we discuss the role of phytochemicals in preventing ovarian cancer through anti-inflammatory mechanisms.

KW - Anti-inflammation

KW - Chemoprevention

KW - Ovarian cancer

KW - Phytochemicals

UR - https://www.scopus.com/pages/publications/79956347718

U2 - 10.1007/s12263-011-0209-y

DO - 10.1007/s12263-011-0209-y

M3 - Review article

AN - SCOPUS:79956347718

SN - 1555-8932

VL - 6

SP - 109

EP - 115

JO - Genes and Nutrition

JF - Genes and Nutrition

IS - 2

ER -

Modulation of inflammatory signaling pathways by phytochemicals in ovarian cancer

Abstract

Keywords

UN SDGs

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