Microheater based on magnetic nanoparticle embedded PDMS

Jeong Ah Kim; Seung Hwan Lee; Hongsuk Park; Jong Hyo Kim; Tai Hyun Park

doi:10.1088/0957-4484/21/16/165102

Microheater based on magnetic nanoparticle embedded PDMS

Jeong Ah Kim, Seung Hwan Lee, Hongsuk Park, Jong Hyo Kim, Tai Hyun Park

Department of Nutritional Science & Food Management

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated to amplify the target DNA (732bp) with > 90% efficiency compared to the conventional PCR thermocycler, and exhibited good performance in regards to temperature control. This system holds great promise for reliably controlling the temperature of thermal processes on an integrated microchip platform for biochemical applications.

Original language	English
Article number	165102
Journal	Nanotechnology
Volume	21
Issue number	16
DOIs	https://doi.org/10.1088/0957-4484/21/16/165102
State	Published - 2010

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abstract = "A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated to amplify the target DNA (732bp) with > 90% efficiency compared to the conventional PCR thermocycler, and exhibited good performance in regards to temperature control. This system holds great promise for reliably controlling the temperature of thermal processes on an integrated microchip platform for biochemical applications.",

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AB - A microheater was established by embedding magnetic nanoparticles into PDMS (MNP-PDMS). MNP-PDMS generated heat under an AC magnetic field and the temperature was controlled by varying the magnetic particle content and the magnetic field intensity. In this study, the MNP-PDMS chip was demonstrated to amplify the target DNA (732bp) with > 90% efficiency compared to the conventional PCR thermocycler, and exhibited good performance in regards to temperature control. This system holds great promise for reliably controlling the temperature of thermal processes on an integrated microchip platform for biochemical applications.

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Microheater based on magnetic nanoparticle embedded PDMS

Abstract

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