Microfluidic solution isolated pumping (μSIP)

Jixiao Liu, Debkishore Mitra, John R. Waldeisen, Richard H. Henrikson, Younggeun Park, Songjing Li, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

A user-friendly, self-contained microfluidic pump is reported which utilizes the high air permeability of PDMS to actuate fluid flow. By diffusion barrier, the solution is isolated from the pump, which provides an innovative solution to create a bubble-free pumping without auxiliary equipment or pre-treatment. This method allows filling dead-end channels and chambers. We implemented this system with an integrated thumb-pump for the standalone operation of microfluidic circuits. A theoretical model was developed and experimentally validated to identify key design parameters and characterize this techniques reproducibility and tunability, achieving flow velocities ranging from 0.7 to 7 mm/sec.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages651-653
Number of pages3
ISBN (Print)9781632666246
StatePublished - 2013
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: 27 Oct 201331 Oct 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume1

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Country/TerritoryGermany
CityFreiburg
Period27/10/1331/10/13

Keywords

  • Bubble-free fluid pump
  • Dead-end channels
  • Lab-on-chip
  • Point-of-care diagnostics

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