TY - JOUR
T1 - Metabolomic differentiation of deer antlers of various origins by 1H NMR spectrometry and principal components analysis
AU - Choi, Hyung Kyoon
AU - Kim, Kyoung Hee
AU - Kim, Kyoung Heon
AU - Kim, Young Suk
AU - Lee, Min Won
AU - Whang, Wan Kyun
PY - 2006/6/7
Y1 - 2006/6/7
N2 - The metabolomic analysis of various types of deer antler was performed by 1H NMR spectrometry and principal components analysis (PCA). The PCA of the 1H NMR spectra of the aqueous fractions allowed a clear discrimination between antler samples according to their origins by the first three principal components (PC1, PC2, and PC3), which cumulatively accounted for 93.5% of the variation in all variables. In particular, the score plots by the combination of PC1 and PC3 allowed an excellent separation of the antler samples. In addition, the major peaks in 1H NMR spectra contributing to the discrimination were assigned to lactate, alanine, acetic acid, choline, glycine, valine, tyrosine, and phenylalanine. This metabolomic-analysis-based method allows various types of deer antler to be efficiently differentiated without any pre-purification steps.
AB - The metabolomic analysis of various types of deer antler was performed by 1H NMR spectrometry and principal components analysis (PCA). The PCA of the 1H NMR spectra of the aqueous fractions allowed a clear discrimination between antler samples according to their origins by the first three principal components (PC1, PC2, and PC3), which cumulatively accounted for 93.5% of the variation in all variables. In particular, the score plots by the combination of PC1 and PC3 allowed an excellent separation of the antler samples. In addition, the major peaks in 1H NMR spectra contributing to the discrimination were assigned to lactate, alanine, acetic acid, choline, glycine, valine, tyrosine, and phenylalanine. This metabolomic-analysis-based method allows various types of deer antler to be efficiently differentiated without any pre-purification steps.
KW - H NMR
KW - Deer antler
KW - Metabolomic analysis
KW - Principal component analysis
UR - http://www.scopus.com/inward/record.url?scp=33646415922&partnerID=8YFLogxK
U2 - 10.1016/j.jpba.2006.01.036
DO - 10.1016/j.jpba.2006.01.036
M3 - Article
C2 - 16495028
AN - SCOPUS:33646415922
SN - 0731-7085
VL - 41
SP - 1047
EP - 1050
JO - Journal of Pharmaceutical and Biomedical Analysis
JF - Journal of Pharmaceutical and Biomedical Analysis
IS - 3
ER -