Abstract
Meroterpenoids, meroindenon (1) and merochlorins E (2) and F (3), were isolated from a marine-derived bacterium belonging to the genus Streptomyces. Their chemical structures were established using extensive analysis of MS, UV, ECD, and NMR spectroscopic data. Compounds 1-3 possess a tetrahydroxynaphthalene core and a C15-isoprene unit. Compounds 2 and 3 exhibited strong antibacterial activities against B. subtilis, K. rhizophila, and S. aureus, with a range of MIC values from 1 to 2 μg/mL.
Original language | English |
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Pages (from-to) | 5779-5783 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 21 |
Issue number | 15 |
DOIs | |
State | Published - 2 Aug 2019 |
Bibliographical note
Publisher Copyright:Copyright © 2019 American Chemical Society.