Abstract
An artificial fusion system was developed in which triazole ceramide was generated at the surface of a liposome membrane through the action of Cu+. The stressed vesicle underwent membrane fusion. The results suggest that curvature inversion alone might be a sufficient driving force for membrane fusion. In addition, our fusion system is cytocompatible and has potential applications in biomedical research.
Original language | English |
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Pages (from-to) | 1713-1717 |
Number of pages | 5 |
Journal | Asian Journal of Organic Chemistry |
Volume | 8 |
Issue number | 9 |
DOIs | |
State | Published - 1 Sep 2019 |
Bibliographical note
Publisher Copyright:© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords
- Ceramide
- Click chemistry
- Liposomes
- Membrane fusion
- Triazole