TY - JOUR
T1 - Maximal pericoronary adipose tissue thickness is associated with hypertension in nonobese patients with acute or chronic illness
AU - Chang, Shinhae
AU - Lee, Wangjin
AU - Kwag, Byounggyu
AU - Chung, Yun Hee
AU - Kang, In Sook
N1 - Publisher Copyright:
© 2017 The Korean Association of Internal Medicine.
PY - 2017/7
Y1 - 2017/7
N2 - Background/Aims: Recent studies have shown an association of epicardial fat thickness with diabetes and hypertension (HTN) in asymptomatic populations. However, there is lack of information as to whether there is similar association between pericoronary adipose tissue (PAT) and HTN in the patients who have acute or chronic illness. Methods: This study included 214 nonobese patients hospitalized with acute or chronic noncardiogenic illness. PAT thicknesses were measured from fat tissues surrounding left and right coronary arteries in enhanced, chest computed tomography scans, yielding the maximal PAT value from left and right coronary arteries was used for analysis. Baseline data from hypertensive (n = 81) and nor-motensive (n = 133) patients were collected and compared. Results: PAT is positively correlated with age (r = 0.377, p <0.001), body mass index (BMI; r = 0.305, p < 0.001), systolic blood pressure (r = 0.216, p = 0.001), and total cholesterol (r = 0.200, p = 0.006). The hypertensive group was older (69.58 ± 11.69 years vs. 60.29 ± 14.98 years), and had higher PAT content (16.30 ± 5.37 mm vs. 13.06 ± 5.58 mm) and BMI (23.14 ± 3.32 kg/m² vs. 20.96 ± 3.28 kg/m²) than the normoten-sive group (all p < 0.001). Multivariate analysis showed that age (odds ratio [OR], 2.193; p = 0.016), PAT thickness (OR, 1.065; p = 0.041), and BMI (25 ≤ BMI < 30 kg/m2; OR, 6.077; p = 0.001) were independent risk factors for HTN. Conclusions: In nonobese patients with noncardiogenic acute or chronic illness, PAT thickness is independently correlated with HTN, age, and BMI.
AB - Background/Aims: Recent studies have shown an association of epicardial fat thickness with diabetes and hypertension (HTN) in asymptomatic populations. However, there is lack of information as to whether there is similar association between pericoronary adipose tissue (PAT) and HTN in the patients who have acute or chronic illness. Methods: This study included 214 nonobese patients hospitalized with acute or chronic noncardiogenic illness. PAT thicknesses were measured from fat tissues surrounding left and right coronary arteries in enhanced, chest computed tomography scans, yielding the maximal PAT value from left and right coronary arteries was used for analysis. Baseline data from hypertensive (n = 81) and nor-motensive (n = 133) patients were collected and compared. Results: PAT is positively correlated with age (r = 0.377, p <0.001), body mass index (BMI; r = 0.305, p < 0.001), systolic blood pressure (r = 0.216, p = 0.001), and total cholesterol (r = 0.200, p = 0.006). The hypertensive group was older (69.58 ± 11.69 years vs. 60.29 ± 14.98 years), and had higher PAT content (16.30 ± 5.37 mm vs. 13.06 ± 5.58 mm) and BMI (23.14 ± 3.32 kg/m² vs. 20.96 ± 3.28 kg/m²) than the normoten-sive group (all p < 0.001). Multivariate analysis showed that age (odds ratio [OR], 2.193; p = 0.016), PAT thickness (OR, 1.065; p = 0.041), and BMI (25 ≤ BMI < 30 kg/m2; OR, 6.077; p = 0.001) were independent risk factors for HTN. Conclusions: In nonobese patients with noncardiogenic acute or chronic illness, PAT thickness is independently correlated with HTN, age, and BMI.
KW - Adipose tissue
KW - Coronary vessels
KW - Hypertension
KW - Multidetector computed tomography
UR - http://www.scopus.com/inward/record.url?scp=85025172710&partnerID=8YFLogxK
U2 - 10.3904/kjim.2016.118
DO - 10.3904/kjim.2016.118
M3 - Article
C2 - 27919158
AN - SCOPUS:85025172710
SN - 1226-3303
VL - 32
SP - 668
EP - 674
JO - Korean Journal of Internal Medicine
JF - Korean Journal of Internal Medicine
IS - 4
ER -