Management of Steroid-Induced Glaucoma in a Patient with Pyoderma Gangrenosum

Ji Yeon Byun, Yong Koo Kang, Yong Hyun Jang, Young Kook Kim, Dai Woo Kim

Research output: Contribution to journalArticlepeer-review


Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder typically presenting as painful skin ulcers, which may also exhibit extracutaneous findings. PG can occur at the site of trauma or surgery, which is known as the pathergic phenomenon. A 36-year-old man developed bilateral steroid-induced glaucoma after prolonged systemic immunosuppressive treatment for cutaneous pyoderma gangrenosum. After successful Ahmed glaucoma valve implantation surgery with donor scleral patch graft in the right eye, the same surgery failed repeatedly in the left eye and complicated with the prolonged conjunctival necrosis and the exposure of the donor scleral patch graft. Under the impression of ocular involvement of PG, microinvasive glaucoma surgery (MIGS) with XEN® Gel Stent was performed in the left eye; the conjunctival bleb was successfully formed without conjunctival necrosis, and intraocular pressure was well maintained. Ophthalmic surgery can be complicated in patients with PG, and the surgical option should be selected prudently to minimize surgical trauma. MIGS, as a minimally invasive surgical technique, could offer an advantage for patients with PG.

Original languageEnglish
Article number2930
JournalJournal of Clinical Medicine
Issue number8
StatePublished - Apr 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.


  • Ahmed glaucoma valve
  • glaucoma
  • microinvasive glaucoma surgery
  • pyoderma gangrenosum


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