Localized optical activation of therapeutic gene release in breast cancer cells using photothermal nanocrescents as oligonucleotide-carriers

Eunice S. Lee, Gang L. Liu, Franklin J. Kim, Angelee Kumar, Luke P. Lee

Research output: Contribution to conferencePaperpeer-review

Abstract

Optical activation of photothermal nanoparticles permits remotely-triggered surface biomolecular reactions with high spatiotemporal resolution. We present a new method to selectively and locally control protein expression by internalizing photothermal nanocrescent particles carrying therapeutic genes within living cells.

Original languageEnglish
Pages284-286
Number of pages3
StatePublished - 2006
Event10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
Duration: 5 Nov 20069 Nov 2006

Conference

Conference10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/TerritoryJapan
CityTokyo
Period5/11/069/11/06

Keywords

  • Gene delivery
  • Molecular nanomedicine
  • Photothermal nanoparticles

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