Localized malignant pleural sarcomatoid mesothelioma misdiagnosed as benign localized fibrous tumor

Kwan Chang Kim, Hong Phuc Vo

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Localized malignant pleural mesothelioma (LMPM) is a rare tumor with good prognosis by surgical resection. We report an atypical case of malignant pleural sarcomatoid mesothelioma (SM) in an asymptomatic 65-year-old woman, who had no history of exposure to asbestos. She presented with a small pleural mass without pleural effusion and was misdiagnosed as a benign localized fibrous tumor (BLFT) on pathologic examination through a surgical tumor specimen. However, seven months later, the patient returned with serious cancerous symptoms. A large recurrent tumor mass was found within the chest wall invading at the old surgical resection site. SM, a subtype of LMPM, was confirmed with histopathogy and immunohistochemisty. In conclusion, malignant pleural mesothelioma (MPM) can present with typical radiologic finding similar to a BLFT, and has a wide histopathologic presentation in biopsy specimen. A thorough pathologic investigation should be attempted even when a pleural mass resembles benign, localized, and small on radiologic studies.

Original languageEnglish
Pages (from-to)E379-E384
JournalJournal of Thoracic Disease
Volume8
Issue number6
DOIs
StatePublished - 1 Jun 2016

Keywords

  • Computed tomography (CT)
  • Lobectomy
  • Mesothelioma
  • Pathology
  • Pleura

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