@inproceedings{9098588a20fe48c0a9bc27b4e4645a13,
title = "Large scale single cell analysis using high density hydrodynamic trapping arrays",
abstract = "This paper reports a novel approach for performing large scale single cell analysis which has significant advantages over miniaturized flow cytometry and laser scanning cytometry (LSC). Regular trapping arrays allow for high density analysis and ease image processing. Moreover, on-chip sample preparation (e.g. fluorescent labeling, washing) is performed, as opposed to manual intensive operations of incubation, centrifugation, and resuspension in previous techniques - saving time and reagents. Additionally, time-dependent phenomena of a large number of single cells over different time scales are characterized using this device. This method is well-suited to quantitative systems biology and rapid medical diagnostics.",
keywords = "Cell array, Cytoenzymology, Quantitative biology, Single cell trapping",
author = "{Di Carlo}, Dino and Nima Aghdam and Hung, {Paul J.} and Lee, {Luke P.}",
year = "2005",
language = "English",
isbn = "0974361119",
series = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Transducer Research Foundation",
pages = "379--381",
booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference",
note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",
}