Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Min Sun Choi; Minji Yoon; Jin Ook Baeg; Jinheung Kim

doi:10.1039/b915994k

Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Min Sun Choi, Minji Yoon, Jin Ook Baeg, Jinheung Kim

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

A homogeneous assay is reported using Ru(phen)₂(dppz) ²⁺ and a K⁺-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K⁺.

Original language	English
Pages (from-to)	7419-7421
Number of pages	3
Journal	Chemical Communications
Issue number	47
DOIs	https://doi.org/10.1039/b915994k
State	Published - 2009

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title = "Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex",

abstract = "A homogeneous assay is reported using Ru(phen)2(dppz) 2+ and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.",

author = "{Sun Choi}, Min and Minji Yoon and Baeg, {Jin Ook} and Jinheung Kim",

year = "2009",

doi = "10.1039/b915994k",

language = "English",

pages = "7419--7421",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

number = "47",

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T1 - Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

AU - Sun Choi, Min

AU - Yoon, Minji

AU - Baeg, Jin Ook

AU - Kim, Jinheung

PY - 2009

Y1 - 2009

N2 - A homogeneous assay is reported using Ru(phen)2(dppz) 2+ and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.

AB - A homogeneous assay is reported using Ru(phen)2(dppz) 2+ and a K+-binding aptamer for the selective and sensitive detection of a target oligonucleotide and potassium ions, based on reduction in fluorescence emission according to the formation of the G-quadruplex structure from the aptamer in the presence of K+.

UR - http://www.scopus.com/inward/record.url?scp=72649090186&partnerID=8YFLogxK

U2 - 10.1039/b915994k

DO - 10.1039/b915994k

M3 - Article

C2 - 20024248

AN - SCOPUS:72649090186

SN - 1359-7345

SP - 7419

EP - 7421

JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

Label-free dual assay of DNA sequences and potassium ions using an aptamer probe and a molecular light switch complex

Abstract

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