Korean Observational Study Network for Arthritis (KORONA): Establishment of a Prospective Multicenter Cohort for Rheumatoid Arthritis in South Korea

Yoon Kyoung Sung, Soo Kyung Cho, Chan Bum Choi, So Yeon Park, Jeeseon Shim, Joong Kyong Ahn, So Young Bang, Hoon Suk Cha, Jung Yoon Choe, Won Tae Chung, Minyoung Her, Seung Jae Hong, Yun Kyung Hong, Chung Il Joung, Jae Bum Jun, Young Ok Jung, Young Mo Kang, Dong Yook Kim, Hae Rim Kim, Hyoun Ah KimJinseok Kim, Seong Kyu Kim, Sung Il Kim, Tae Hwan Kim, Tae Jong Kim, Eunmi Koh, Choong Ki Lee, Hye Soon Lee, Jisoo Lee, Sang Heon Lee, Sang Hoon Lee, Shin Seok Lee, Sung Won Lee, Yeon Ah Lee, Seong Su Nah, Sung Hoon Park, Dong Hyuk Sheen, Seung Cheol Shim, Gwan Gyu Song, Chang Hee Suh, Wan Sik Uhm, Dae Hyun Yoo, Wan Hee Yoo, Bo Young Yoon, Sang Cheol Bae

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Objectives: The object of this study was to introduce the KORean Observational study Network for Arthritis (KORONA) registry with an emphasis on the design of the Korean rheumatoid arthritis (RA) national database, as well as to provide an overview of the RA patients who are currently registered in KORONA. Methods: The KORONA was established in July 2009 by the Clinical Research Center for Rheumatoid Arthritis (CRCRA) in South Korea. KORONA is based on a prospective protocol and standard, defined data collection instruments. Demographic and clinical features, laboratory and radiologic data, health-related outcomes, treatment side effects, resource utilization, and health behaviors of the RA cohort patients are recorded in a database. Results: A total of 23 institutions, which are about 38% of the rheumatologic departments at tertiary academic hospitals across South Korea, are part of KORONA. The quality control of data collection and management has been performed through annual monitoring and auditing, staff training, and providing standard operation protocol by the executive committee of CRCRA. As of 31 December 2010, 4721 patients with established RA were included in KORONA, because an annual survey had started to be performed in July 2010. Conclusions: KORONA is the first nationwide Korean RA-specific cohort and it will provide valuable "real-world" information for Korean RA patients.

Original languageEnglish
Pages (from-to)745-751
Number of pages7
JournalSeminars in Arthritis and Rheumatism
Issue number6
StatePublished - Jun 2012


  • Cohort study
  • Prospective study
  • Rheumatoid arthritis


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