KAAACI evidence-based clinical practice guidelines for chronic cough in adults and children in Korea

Dae Jin Song, Woo Jung Song, Jae Woo Kwon, Gun Woo Kim, Mi Ae Kim, Mi Yeong Kim, Min Hye Kim, Sang Ha Kim, Sang Heon Kim, Sang Hyuck Kim, Sun Tae Kim, Sae Hoon Kim, Ja Kyoung Kim, Joo Hee Kim, Hyun Jung Kim, Hyo Bin Kim, Kyung Hee Park, Jae Kyun Yoon, Byung Jae Lee, Seung Eun LeeYoung Mok Lee, Yong Ju Lee, Kyung Hwan Lim, You Hoon Jeon, Eun Jung Jo, Young Koo Jee, Hyun Jung Jin, Sun Hee Choi, Gyu Young Hur, Sang Heon Cho, Sang Hoon Kim, Dae Hyun Lim

Research output: Contribution to journalReview articlepeer-review

54 Scopus citations


Chronic cough is common in the community and causes significant morbidity. Several factors may underlie this problem, but comorbid conditions located at sensory nerve endings that regulate the cough reflex, including rhinitis, rhinosinusitis, asthma, eosinophilic bronchitis, and gastroesophageal reflux disease, are considered important. However, chronic cough is frequently non-specific and accompanied by not easily identifiable causes during the initial evaluation. Therefore, there are unmet needs for developing empirical treatment and practical diagnostic approaches that can be applied in primary clinics. Meanwhile, in referral clinics, a considerable proportion of adult patients with chronic cough are unexplained or refractory to conventional treatment. The present clinical practice guidelines aim to address major clinical questions regarding empirical treatment, practical diagnostic tools for non-specific chronic cough, and available therapeutic options for chronic wet cough in children and unexplained chronic cough in adults in Korea.

Original languageEnglish
Pages (from-to)591-613
Number of pages23
JournalAllergy, Asthma and Immunology Research
Issue number6
StatePublished - 1 Nov 2018

Bibliographical note

Publisher Copyright:
© 2018 The Korean Academy of Asthma, Allergy and Clinical Immunology · The Korean Academy of Pediatric Allergy and Respiratory Disease.


  • Cough
  • Evidence-based medicine
  • Guideline


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