Isolation and characterization of tetracycline-resistant clinical isolates of Helicobacter pylori

D. H. Kwon; J. J. Kim; M. Lee; Y. Yamaoka; M. Kato; M. S. Osato; F. A.K. El-Zaatari; D. Y. Graham

doi:10.1128/AAC.44.11.3203-3205.2000

Isolation and characterization of tetracycline-resistant clinical isolates of Helicobacter pylori

D. H. Kwon
, J. J. Kim
, M. Lee
, Y. Yamaoka
, M. Kato
, M. S. Osato
, F. A.K. El-Zaatari
, D. Y. Graham

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Tetracycline is an important component of combination therapies for Helicobacter pylori eradication. Twenty-nine tetracycline-resistant isolates requiring MICs ranging from 4 to 16 μg/ml were isolated from Korean (22 of 460) and Japanese (7 of 105) patients. Interestingly, all of the 29 tetracycline-resistant isolates exhibited cross-resistance to metronidazole, and the cross-resistance was transferred to tetracycline-sensitive H. pylori strains.

Original language	English
Pages (from-to)	3203-3205
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	44
Issue number	11
DOIs	https://doi.org/10.1128/AAC.44.11.3203-3205.2000
State	Published - 2000

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title = "Isolation and characterization of tetracycline-resistant clinical isolates of Helicobacter pylori",

abstract = "Tetracycline is an important component of combination therapies for Helicobacter pylori eradication. Twenty-nine tetracycline-resistant isolates requiring MICs ranging from 4 to 16 μg/ml were isolated from Korean (22 of 460) and Japanese (7 of 105) patients. Interestingly, all of the 29 tetracycline-resistant isolates exhibited cross-resistance to metronidazole, and the cross-resistance was transferred to tetracycline-sensitive H. pylori strains.",

author = "Kwon, \{D. H.\} and Kim, \{J. J.\} and M. Lee and Y. Yamaoka and M. Kato and Osato, \{M. S.\} and El-Zaatari, \{F. A.K.\} and Graham, \{D. Y.\}",

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AU - Kwon, D. H.

AU - Kim, J. J.

AU - Lee, M.

AU - Yamaoka, Y.

AU - Kato, M.

AU - Osato, M. S.

AU - El-Zaatari, F. A.K.

AU - Graham, D. Y.

PY - 2000

Y1 - 2000

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AB - Tetracycline is an important component of combination therapies for Helicobacter pylori eradication. Twenty-nine tetracycline-resistant isolates requiring MICs ranging from 4 to 16 μg/ml were isolated from Korean (22 of 460) and Japanese (7 of 105) patients. Interestingly, all of the 29 tetracycline-resistant isolates exhibited cross-resistance to metronidazole, and the cross-resistance was transferred to tetracycline-sensitive H. pylori strains.

UR - https://www.scopus.com/pages/publications/0033734822

U2 - 10.1128/AAC.44.11.3203-3205.2000

DO - 10.1128/AAC.44.11.3203-3205.2000

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JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 11

ER -

Isolation and characterization of tetracycline-resistant clinical isolates of Helicobacter pylori

Abstract

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