Described herein is the development of an iridium-catalyzed direct C-H amination of benzamides with anilines at room temperature, representing a unique example of an Ir catalyst system that is compatible with external oxidants. Mechanistic details, such as the isolation and characterization of key iridacycle intermediates, are also discussed.
|Number of pages||4|
|Journal||Journal of the American Chemical Society|
|State||Published - 23 Apr 2014|