Invasive pulmonary aspergillosis after influenza a infection in an immunocompetent patient

Oh Kyung Kwon, Myung Goo Lee, Hyo Sun Kim, Min Sun Park, Kyoung Min Kwak, So Young Park

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Invasive aspergillosis has emerged as a major cause of life-threatening infections in immunocompromised patients. Recently, patients with chronic obstructive pulmonary disease, who have been receiving corticosteroids for a long period, and immunocompetent patients in the intensive care unit have been identified as nontraditional hosts at risk for invasive aspergillosis. Here, we report a case of invasive pulmonary aspergillosis after influenza in an immunocompetent patient. The patient's symptoms were nonspecific, and the patient was unresponsive to treatments for pulmonary bacterial infection. Bronchoscopy revealed mucosa hyperemia, and wide, raised and cream-colored plaques throughout the trachea and both the main bronchi. Histologic examination revealed aspergillosis. The patient recovered quickly when treated systemically with voriconazole, although the reported mortality rates for aspergillosis are extremely high. This study showed that invasive aspergillosis should be considered in immunocompetent patients who are unresponsive to antibiotic treatments; further, early extensive use of all available diagnostic tools, especially bronchoscopy, is mandatory.

Original languageEnglish
Pages (from-to)260-263
Number of pages4
JournalTuberculosis and Respiratory Diseases
Issue number6
StatePublished - Dec 2013


  • Immunocompetence
  • Influenza A Virus
  • Invasive Pulmonary Aspergillosis


Dive into the research topics of 'Invasive pulmonary aspergillosis after influenza a infection in an immunocompetent patient'. Together they form a unique fingerprint.

Cite this