Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety

Kiyoshi Fukuhara; Ikuo Nakanishi; Kei Ohkubo; Yoshinori Obara; Ayako Tada; Kohei Imai; Akiko Ohno; Asao Nakamura; Toshihiko Ozawa; Shiro Urano; Shinichi Saito; Shunichi Fukuzumi; Kazunori Anzai; Naoki Miyata; Haruhiro Okuda

doi:10.1039/b913714a

Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety

Kiyoshi Fukuhara, Ikuo Nakanishi, Kei Ohkubo, Yoshinori Obara, Ayako Tada, Kohei Imai, Akiko Ohno, Asao Nakamura, Toshihiko Ozawa, Shiro Urano, Shinichi Saito, Shunichi Fukuzumi, Kazunori Anzai, Naoki Miyata, Haruhiro Okuda

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A planar catechin derivative incorporating a lysine moiety was synthesized and showed ∼400-fold increased radical-scavenging activity relative to naturally-occurring (+)-catechin.

Original language	English
Pages (from-to)	6180-6182
Number of pages	3
Journal	Chemical Communications
Issue number	41
DOIs	https://doi.org/10.1039/b913714a
State	Published - 2009

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Fukuhara, K., Nakanishi, I., Ohkubo, K., Obara, Y., Tada, A., Imai, K., Ohno, A., Nakamura, A., Ozawa, T., Urano, S., Saito, S., Fukuzumi, S., Anzai, K., Miyata, N., & Okuda, H. (2009). Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety. Chemical Communications, (41), 6180-6182. https://doi.org/10.1039/b913714a

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title = "Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety",

abstract = "A planar catechin derivative incorporating a lysine moiety was synthesized and showed ∼400-fold increased radical-scavenging activity relative to naturally-occurring (+)-catechin.",

author = "Kiyoshi Fukuhara and Ikuo Nakanishi and Kei Ohkubo and Yoshinori Obara and Ayako Tada and Kohei Imai and Akiko Ohno and Asao Nakamura and Toshihiko Ozawa and Shiro Urano and Shinichi Saito and Shunichi Fukuzumi and Kazunori Anzai and Naoki Miyata and Haruhiro Okuda",

year = "2009",

doi = "10.1039/b913714a",

language = "English",

pages = "6180--6182",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety

AU - Fukuhara, Kiyoshi

AU - Nakanishi, Ikuo

AU - Ohkubo, Kei

AU - Obara, Yoshinori

AU - Tada, Ayako

AU - Imai, Kohei

AU - Ohno, Akiko

AU - Nakamura, Asao

AU - Ozawa, Toshihiko

AU - Urano, Shiro

AU - Saito, Shinichi

AU - Fukuzumi, Shunichi

AU - Anzai, Kazunori

AU - Miyata, Naoki

AU - Okuda, Haruhiro

PY - 2009

Y1 - 2009

N2 - A planar catechin derivative incorporating a lysine moiety was synthesized and showed ∼400-fold increased radical-scavenging activity relative to naturally-occurring (+)-catechin.

AB - A planar catechin derivative incorporating a lysine moiety was synthesized and showed ∼400-fold increased radical-scavenging activity relative to naturally-occurring (+)-catechin.

UR - http://www.scopus.com/inward/record.url?scp=70349973232&partnerID=8YFLogxK

U2 - 10.1039/b913714a

DO - 10.1039/b913714a

M3 - Article

C2 - 19826661

AN - SCOPUS:70349973232

SN - 1359-7345

SP - 6180

EP - 6182

JO - Chemical Communications

JF - Chemical Communications

IS - 41

ER -

Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety

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