Intracranial EEG surface renderings: New insights into normal and abnormal brain function

Mark W. Youngblood, Xiao Han, Pue Farooque, Stephen Jhun, Xiaoxiao Bai, Ji Yeoun Yoo, Hyang Woon Lee, Hal Blumenfeld

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Intracranial electro-encephalography (icEEG) provides a unique opportunity to record directly from the human brain and is clinically important for planning epilepsy surgery. However, traditional visual analysis of icEEG is often challenging. The typical simultaneous display of multiple electrode channels can prevent an in-depth understanding of the spatial-time course of brain activity. In recent decades, advances in the field of neuroimaging have provided powerful new tools for the analysis and display of signals in the brain. These methods can now be applied to icEEG to map electrical signal information onto a three-dimensional rendering of a patient's cortex and graphically observe the changes in voltage over time. This approach provides rapid visualization of seizures and normal activity propagating over the brain surface and can also illustrate subtle changes that might be missed by traditional icEEG analysis. In addition, the direct mapping of signal information onto accurate anatomical structures can assist in the precise targeting of sites for epilepsy surgery and help correlate electrical activity with behavior. Bringing icEEG data into a standardized anatomical space will also enable neuroimaging methods of statistical analysis to be applied. As new technologies lead to a dramatic increase in the rate of data acquisition, these novel visualization and analysis techniques will play an important role in processing the valuable information obtained through icEEG.

Original languageEnglish
Pages (from-to)238-247
Number of pages10
Issue number3
StatePublished - Jun 2013

Bibliographical note

Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by NIH R01NS055829, R01NS066974, R01MH67528, R01HL059619, P30NS052519, U01NS045911, CTSA UL1 RR0249139, a Donaghue Foundation Investigator Award, and the Betsy and Jonathan Blattmachr Family [HB]; as well as by the Ewha Global Top 5 Grant 2011 of Ewha Womans University and the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology [R01-2011-0015788 to HWL].


  • cortical power projections
  • data visualization
  • intracranial EEG


Dive into the research topics of 'Intracranial EEG surface renderings: New insights into normal and abnormal brain function'. Together they form a unique fingerprint.

Cite this