Interrupting specific hydrogen bonds between ELF3 and MED23 as an alternative drug resistance-free strategy for HER2-overexpressing cancers

Medicine and Dentistry

• Antineoplastic Activity 100%
• Drug Resistance 100%
• Trastuzumab 100%
• In Vitro 50%
• Breast Cancer 50%
• Genetic Transcription 50%
• Recurrent Disease 50%
• Carcinogenesis 50%
• In Silico 50%
• Solid Malignant Neoplasm 50%
• Tumor Xenograft 50%
• Fluorescence Polarization 50%
• Tandem Mass Spectrometry 50%
• Liquid Chromatography-Mass Spectrometry 50%
• Gene Amplification 50%
• Cell Culture 50%

Biochemistry, Genetics and Molecular Biology

• Hydrogen Bond 100%
• Small Molecule 100%
• Antineoplastic Activity 100%
• Drug Resistance 100%
• Trastuzumab 100%
• Mouse Model 50%
• Tandem Mass Spectrometry 50%
• Gene Amplification 50%
• Cell Culture 50%
• Genetic Transcription 50%
• Carcinogenesis 50%
• Liquid Chromatography-Mass Spectrometry 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Hydrogen Bond 100%
• Drug Resistance 100%
• Trastuzumab 100%
• Mouse Model 50%
• Cell Culture 50%
• Breast Cancer 50%
• Recurrent Disease 50%
• Solid Malignant Neoplasm 50%
• Neoplasm 50%
• Carcinogenesis 50%