Inter-observer agreement on the interpretation of capsule endoscopy findings based on capsule endoscopy structured terminology: A multicenter study by the Korean gut image study group

Byung Ik Jang, Si Hyung Lee, Jeong Seop Moon, Dae Young Cheung, In Seok Lee, Jin Oh Kim, Jae Hee Cheon, Cheol Hee Park, Jeong Sik Byeon, Youn Sun Park, Ki Nam Shim, Yong Sik Kim, Kyung Jo Kim, Kwang Jae Lee, Ji Kon Ryu, Dong Kyung Chang, Hoon Jai Chun, Myung Gyu Choi

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Objective. Capsule endoscopy (CE) is a novel investigation for the diagnosis of small-bowel disease but its interpretation is highly subjective. We studied the inter-observer agreement and accuracy of the interpretation of CE findings based on capsule endoscopy structured terminology (CEST). Material and methods. Fifty-six CE video clips were collected from eight university hospitals in South Korea and were independently reviewed by 13 gastroenterology experts and 10 trainees. All investigators recorded their findings based on CEST. To determine the accuracy of individual viewers, we defined the 'gold standard' as a joint review by four experts. Results. The 56 CE video clips included five normal cases, 19 cases of protruding lesions, 21 cases of depressed lesions, three cases of flat lesions, one case of abnormal mucosa, six cases with blood in the lumen, and one case of stenotic lumen. The overall mean accuracies for the experts and trainees were 74.3% ± 22.6% and 61.7% ± 25.4%, respectively. The overall accuracy for the trainee group was significantly lower than that for the expert group (P<0.001), especially in normal, tumor, venous structure, and ulcer cases. The accuracies of the two groups varied with the CE findings. The accuracies were higher in cases with more prominent intraluminal changes (e.g. active small-bowel bleeding, ulcer, tumor, stenotic lumen). In contrast, subtle mucosal lesions, such as erosion, angioectasia, and diverticulum, had lower accuracies. The mean kappa values for the experts and trainees were 0.61 (range 0.390.97) and 0.46 (range 0.170.66), respectively. Conclusions. Our results showed that there was substantial agreement between experts and moderate agreement between trainees. In order to achieve higher accuracies and better inter-observer agreement, we need not only more experience with CE but also consensus regarding CEST terminology.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalScandinavian Journal of Gastroenterology
Volume45
Issue number3
DOIs
StatePublished - 2010

Keywords

  • Capsule endoscopy analysis
  • Inter-observer variability
  • Small-bowel lesions

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