Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

Kyubo Kim, Minsoo Chun, Hyeongmin Jin, Wonguen Jung, Kyung Hwan Shin, Seong Soo Shin, Yeon Joo Kim, Shin Hyung Park, Jin Hee Kim, Yong Ho Kim, Hyun Soo Shin, Haeyoung Kim, Su Ssan Kim, Jong Hoon Lee, Yong Bae Kim, Sun Young Lee, Jinhyun Choi, Do Hoon Oh, Ki Mun Kang, Jeanny KwonMi Young Kim, Taeryool Koo, Hae Jin Park, Sung Ja Ahn

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background/Aim: To present the variations in the target delineation and the planning results of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods: We requested the target volumes and organs at risk delineation for two cases of left breast cancers, and evaluated the IMRT plans including the supraclavicular and internal mammary node irradiation. Results: Twenty-one institutions participated in this study. Differences in the planning target volume among institutions reached up to three-times for breast-conserving surgery (BCS) case and five-times for mastectomy case. Mean heart doses ranged from 3.3 to 24.1 Gy for BCS case and from 5.0 to 26.5 Gy for mastectomy case. Ipsilateral lung volumes receiving more than 20 Gy ranged from 4.7 to 57.4% for BCS case and from 16.4 to 55.5% for mastectomy case. Conclusion: There were large variations in the target delineation and planning results of IMRT for breast cancers among institutions. Considering the increased use of breast IMRT, more standardized protocols are needed.

Original languageEnglish
Pages (from-to)3145-3152
Number of pages8
JournalAnticancer Research
Volume41
Issue number6
DOIs
StatePublished - Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 International Institute of Anticancer Research. All rights reserved.

Keywords

  • Breast cancer
  • Dose-volume constraint
  • Intensity-modulated radiation therapy
  • Target volume
  • Variation

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