TY - JOUR
T1 - Intensive blood pressure lowering
T2 - a practical review
AU - Camafort, Miguel
AU - Redón, Josep
AU - Pyun, Wook Bum
AU - Coca, Antonio
N1 - Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - According to the last Hypertension guideline recommendations, it may be concluded that intensive BP lowering is only advisable in a subgroup of patients where there is a clear net benefit of targeting to lower BP goals. However, taking into account the relevance of correct BP measurement, estimates of the benefits versus the harm should be based on reliable office BP measurements and home BP measurements. There is still debate about which BP goals are optimal in reducing morbidity and mortality in uncomplicated hypertensives and in those with associated comorbidities. In recent years, trials and meta-analyses have assessed intensive BP lowering, with some success. However, a careful examination of the results shows that current data are not easily applicable to the general hypertensive population. This article reviews the evidence on and controversies about intensive BP lowering in general and in specific clinical situations, and the importance of obtaining reliable BP readings in patients with hypertension and comorbidities.
AB - According to the last Hypertension guideline recommendations, it may be concluded that intensive BP lowering is only advisable in a subgroup of patients where there is a clear net benefit of targeting to lower BP goals. However, taking into account the relevance of correct BP measurement, estimates of the benefits versus the harm should be based on reliable office BP measurements and home BP measurements. There is still debate about which BP goals are optimal in reducing morbidity and mortality in uncomplicated hypertensives and in those with associated comorbidities. In recent years, trials and meta-analyses have assessed intensive BP lowering, with some success. However, a careful examination of the results shows that current data are not easily applicable to the general hypertensive population. This article reviews the evidence on and controversies about intensive BP lowering in general and in specific clinical situations, and the importance of obtaining reliable BP readings in patients with hypertension and comorbidities.
KW - Ageing
KW - Ambulatory blood pressure measurement
KW - Chronic kidney disease
KW - Diabetes mellitus type 2
KW - Heart failure
KW - Intensive blood pressure lowering
KW - Ischemic heart disease
KW - Obesity, cardiovascular risk
UR - http://www.scopus.com/inward/record.url?scp=85103988710&partnerID=8YFLogxK
U2 - 10.1186/s40885-020-00153-z
DO - 10.1186/s40885-020-00153-z
M3 - Review article
AN - SCOPUS:85103988710
SN - 2056-5909
VL - 26
JO - Clinical Hypertension
JF - Clinical Hypertension
IS - 1
M1 - 21
ER -