Integrated multiple patch-clamp array chip via lateral cell trapping junctions

J. Seo, C. Ionescu-Zanetti, J. Diamond, R. Lal, L. P. Lee

Research output: Contribution to journalArticlepeer-review

105 Scopus citations

Abstract

An integrated multiple patch-clamp array chip via reliable lateral cell trapping junctions was presented. The intersectional design of the microfluidic network provides instantaneous multiple cell addressing. The device geometry results in very low capacitive coupling between the cell reservoir and the patch channel. It was found that the device has the potential for high-throughput, low cost cell-based patch-clamp measurements.

Original languageEnglish
Pages (from-to)1973-1975
Number of pages3
JournalApplied Physics Letters
Volume84
Issue number11
DOIs
StatePublished - 15 Mar 2004

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