Integrated Microalgae Analysis Photobioreactor for Rapid Strain Selection

Soon Gweon Hong, Minsun Song, Sungjun Kim, Doyeon Bang, Taewook Kang, Inhee Choi, Luke P. Lee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Algal photosynthesis is considered to be a sustainable, alternative, and renewable solution to generating green energy. For high-productivity algaculture in diverse local environments, a high-throughput screening method is needed to select algal strains from naturally available or genetically engineered strains. Herein, we present an integrated plasmonic photobioreactor for rapid, high-throughput screening of microalgae. Our 3D nanoplasmonic optical cavity-based photobioreactor permits the amplification of a selective wavelength favorable to photosynthesis in the cavity. The hemispheric plasmonic cavity allows intercellular interaction to be promoted in the optically favorable milieu and also permits effective visual examination of algal growth. Using Chlamydomonas reinhardtii, we demonstrated a 2-fold enhanced growth rate and a 1.5-fold lipid production rate with no distinctive lag phase. By facilitating growth and biomass conversion rates, the integrated microalgae analysis platform will serve as rapid microalgae screening platforms for biofuel applications.

Original languageEnglish
Pages (from-to)5635-5642
Number of pages8
JournalACS Nano
Issue number6
StatePublished - 28 Jun 2016


  • Bioreactor
  • Microalgae
  • Optical cavity
  • Plasmonics
  • Rapid strain selection


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