Abstract
We present a new planar, silicon-based patch clamp array. Each patch site is vertically oriented, which allows simultaneous use of scanning probe, optical, or fluorescent detection technologies. Each microfabricated patch site is also connected to its own fluidic channel so that the array can be used for parallel screening of cells or analysis of tethered lipid membranes or vesicles that express the proteins of interest. A single unit, fully three-dimensional ring-shaped patch clamp recording device has been designed and fabricated.
Original language | English |
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Title of host publication | 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings |
Editors | David Beebe, Andre Dittmar |
Publisher | Institute of Electrical and Electronics Engineers Inc. |
Pages | 71-75 |
Number of pages | 5 |
ISBN (Electronic) | 0780374800, 9780780374805 |
DOIs | |
State | Published - 2002 |
Event | 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Madison, United States Duration: 2 May 2002 → 4 May 2002 |
Publication series
Name | 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology - Proceedings |
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Conference
Conference | 2nd Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology |
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Country/Territory | United States |
City | Madison |
Period | 2/05/02 → 4/05/02 |
Bibliographical note
Publisher Copyright:© 2002 IEEE.
Keywords
- array
- automation
- planar patch clamp