Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002

Kyungwon Lee; Young Ah Kim; Yeon Joon Park; Hye Soo Lee; Moon Yeun Kim; Eui Chong Kim; Dongeun Yong; Yunsop Chong; Jae Seok Kim; Sunjoo Kim; Namhee Ryoo; Hoo Jeong; Gyoung Yim Ha; Chulhun L. Chang; Ki Hyung Park; Nam Yong Lee; Myungshin Kim; Jeong Ho Kim; Joseph Jeong; Ji Hyun Cho; Young Uh; Ki Sook Hong; Moon Bo Shin; Jin Ju Kim; Sook Jin Jang; Ae Ja Park; Young Joo Cha; Young Jin Choi; Ha Kang; Chang Hyun Rhim; Myung Hee Lee; Wonkeun Song; Tae Yeal Choi; Jung Oak Kang; Jong Hee Shin; Seong Geun Hong; Hee Joo Lee; Hwan Sub Lim; Hee Jung Kang; Hyun Kyung Kim; Miae Lee

doi:10.3349/ymj.2004.45.4.598

Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002

Kyungwon Lee, Young Ah Kim, Yeon Joon Park, Hye Soo Lee, Moon Yeun Kim, Eui Chong Kim, Dongeun Yong, Yunsop Chong, Jae Seok Kim, Sunjoo Kim, Namhee Ryoo, Hoo Jeong, Gyoung Yim Ha, Chulhun L. Chang, Ki Hyung Park, Nam Yong Lee, Myungshin Kim, Jeong Ho Kim, Joseph Jeong, Ji Hyun ChoYoung Uh, Ki Sook Hong, Moon Bo Shin, Jin Ju Kim, Sook Jin Jang, Ae Ja Park, Young Joo Cha, Young Jin Choi, Ha Kang, Chang Hyun Rhim, Myung Hee Lee, Wonkeun Song, Tae Yeal Choi, Jung Oak Kang, Jong Hee Shin, Seong Geun Hong, Hee Joo Lee, Hwan Sub Lim, Hee Jung Kang, Hyun Kyung Kim, Miae Lee

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

Continued antimicrobial resistance surveillance can provide valuable information for the empirical selection of antimicrobial agents for patient treatment, and for resistance control. In this 6th annual study for 2002, the susceptibility data at 39 Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) hospitals were analyzed. Resistance rates of S. aureus were 67% to oxacillin, and 58% to clindamycin. The ampicillin and vancomycin resistance rates of E. faecium were 89% and 16%, respectively. To penicillin, 71% of S. pneumoniae were nonsusceptible. Resistance rates of E. coli were 11% to cefotaxime, 8% to cefoxitin, and 34% to fluoroquinolone, and those of K. pneumoniae were 22% to ceftazidime, and 16% to cefoxitin. Lowest resistance rates to cephalosporins shown by E. cloacae and S. marcescens were to cefepime, 7% and 17%, respectively. This is the first KONSAR surveillance, which detected imipenem-resistant E. coli and K. pneumoniae. To imipenem, 22% of P. aeruginosa and 9% of Acinetobacter spp. were resistant. Trends of resistances showed a slight reduction in MRSA and in penicillin-nonsusceptible S. pneumoniae, but an increase in ampicillin-resistant E. faecium. Ampicillin-resistant E. coli and H. influenzae remained prevalent. Compared to the previous study, amikacin- and fluoroquinolone- resistant Acinetobacter spp. increased to 60% and 62%, respectively. Ceftazidime-resistant K. pneumoniae decreased slightly, and imipenem-resistant P. aeruginosa and Acinetobacter spp., and vancomycin-resistant E. faecium increased. In conclusion, vancomycin-resistant E. faecium, cefoxitin-resistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa and Acinetobacter spp. increased gradually, and imipenem-resistant E. coli and K. pneumoniae appeared for the first time. Continued surveillance is required to prevent further spread of these serious resistances.

Original language	English
Pages (from-to)	598-608
Number of pages	11
Journal	Yonsei Medical Journal
Volume	45
Issue number	4
DOIs	https://doi.org/10.3349/ymj.2004.45.4.598
State	Published - 31 Aug 2004

Keywords

Antimicrobial resistance
Imipenem resistance
Korean resistance surveillance

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10.3349/ymj.2004.45.4.598

Cite this

Lee, K., Kim, Y. A., Park, Y. J., Lee, H. S., Kim, M. Y., Kim, E. C., Yong, D., Chong, Y., Kim, J. S., Kim, S., Ryoo, N., Jeong, H., Ha, G. Y., Chang, C. L., Park, K. H., Lee, N. Y., Kim, M., Kim, J. H., Jeong, J., ... Lee, M. (2004). Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002. Yonsei Medical Journal, 45(4), 598-608. https://doi.org/10.3349/ymj.2004.45.4.598

@article{29581e606e8c408bbe048d640b0128c5,

title = "Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002",

abstract = "Continued antimicrobial resistance surveillance can provide valuable information for the empirical selection of antimicrobial agents for patient treatment, and for resistance control. In this 6th annual study for 2002, the susceptibility data at 39 Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) hospitals were analyzed. Resistance rates of S. aureus were 67% to oxacillin, and 58% to clindamycin. The ampicillin and vancomycin resistance rates of E. faecium were 89% and 16%, respectively. To penicillin, 71% of S. pneumoniae were nonsusceptible. Resistance rates of E. coli were 11% to cefotaxime, 8% to cefoxitin, and 34% to fluoroquinolone, and those of K. pneumoniae were 22% to ceftazidime, and 16% to cefoxitin. Lowest resistance rates to cephalosporins shown by E. cloacae and S. marcescens were to cefepime, 7% and 17%, respectively. This is the first KONSAR surveillance, which detected imipenem-resistant E. coli and K. pneumoniae. To imipenem, 22% of P. aeruginosa and 9% of Acinetobacter spp. were resistant. Trends of resistances showed a slight reduction in MRSA and in penicillin-nonsusceptible S. pneumoniae, but an increase in ampicillin-resistant E. faecium. Ampicillin-resistant E. coli and H. influenzae remained prevalent. Compared to the previous study, amikacin- and fluoroquinolone- resistant Acinetobacter spp. increased to 60% and 62%, respectively. Ceftazidime-resistant K. pneumoniae decreased slightly, and imipenem-resistant P. aeruginosa and Acinetobacter spp., and vancomycin-resistant E. faecium increased. In conclusion, vancomycin-resistant E. faecium, cefoxitin-resistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa and Acinetobacter spp. increased gradually, and imipenem-resistant E. coli and K. pneumoniae appeared for the first time. Continued surveillance is required to prevent further spread of these serious resistances.",

keywords = "Antimicrobial resistance, Imipenem resistance, Korean resistance surveillance",

author = "Kyungwon Lee and Kim, {Young Ah} and Park, {Yeon Joon} and Lee, {Hye Soo} and Kim, {Moon Yeun} and Kim, {Eui Chong} and Dongeun Yong and Yunsop Chong and Kim, {Jae Seok} and Sunjoo Kim and Namhee Ryoo and Hoo Jeong and Ha, {Gyoung Yim} and Chang, {Chulhun L.} and Park, {Ki Hyung} and Lee, {Nam Yong} and Myungshin Kim and Kim, {Jeong Ho} and Joseph Jeong and Cho, {Ji Hyun} and Young Uh and Hong, {Ki Sook} and Shin, {Moon Bo} and Kim, {Jin Ju} and Jang, {Sook Jin} and Park, {Ae Ja} and Cha, {Young Joo} and Choi, {Young Jin} and Ha Kang and Rhim, {Chang Hyun} and Lee, {Myung Hee} and Wonkeun Song and Choi, {Tae Yeal} and Kang, {Jung Oak} and Shin, {Jong Hee} and Hong, {Seong Geun} and Lee, {Hee Joo} and Lim, {Hwan Sub} and Kang, {Hee Jung} and Kim, {Hyun Kyung} and Miae Lee",

year = "2004",

month = aug,

day = "31",

doi = "10.3349/ymj.2004.45.4.598",

language = "English",

volume = "45",

pages = "598--608",

journal = "Yonsei Medical Journal",

issn = "0513-5796",

publisher = "Yonsei University College of Medicine",

number = "4",

}

Lee, K, Kim, YA, Park, YJ, Lee, HS, Kim, MY, Kim, EC, Yong, D, Chong, Y, Kim, JS, Kim, S, Ryoo, N, Jeong, H, Ha, GY, Chang, CL, Park, KH, Lee, NY, Kim, M, Kim, JH, Jeong, J, Cho, JH, Uh, Y, Hong, KS, Shin, MB, Kim, JJ, Jang, SJ, Park, AJ, Cha, YJ, Choi, YJ, Kang, H, Rhim, CH, Lee, MH, Song, W, Choi, TY, Kang, JO, Shin, JH, Hong, SG, Lee, HJ, Lim, HS, Kang, HJ, Kim, HK & Lee, M 2004, 'Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002', Yonsei Medical Journal, vol. 45, no. 4, pp. 598-608. https://doi.org/10.3349/ymj.2004.45.4.598

TY - JOUR

T1 - Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli

T2 - A KONSAR Study in 2002

AU - Lee, Kyungwon

AU - Kim, Young Ah

AU - Park, Yeon Joon

AU - Lee, Hye Soo

AU - Kim, Moon Yeun

AU - Kim, Eui Chong

AU - Yong, Dongeun

AU - Chong, Yunsop

AU - Kim, Jae Seok

AU - Kim, Sunjoo

AU - Ryoo, Namhee

AU - Jeong, Hoo

AU - Ha, Gyoung Yim

AU - Chang, Chulhun L.

AU - Park, Ki Hyung

AU - Lee, Nam Yong

AU - Kim, Myungshin

AU - Kim, Jeong Ho

AU - Jeong, Joseph

AU - Cho, Ji Hyun

AU - Uh, Young

AU - Hong, Ki Sook

AU - Shin, Moon Bo

AU - Kim, Jin Ju

AU - Jang, Sook Jin

AU - Park, Ae Ja

AU - Cha, Young Joo

AU - Choi, Young Jin

AU - Kang, Ha

AU - Rhim, Chang Hyun

AU - Lee, Myung Hee

AU - Song, Wonkeun

AU - Choi, Tae Yeal

AU - Kang, Jung Oak

AU - Shin, Jong Hee

AU - Hong, Seong Geun

AU - Lee, Hee Joo

AU - Lim, Hwan Sub

AU - Kang, Hee Jung

AU - Kim, Hyun Kyung

AU - Lee, Miae

PY - 2004/8/31

Y1 - 2004/8/31

N2 - Continued antimicrobial resistance surveillance can provide valuable information for the empirical selection of antimicrobial agents for patient treatment, and for resistance control. In this 6th annual study for 2002, the susceptibility data at 39 Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) hospitals were analyzed. Resistance rates of S. aureus were 67% to oxacillin, and 58% to clindamycin. The ampicillin and vancomycin resistance rates of E. faecium were 89% and 16%, respectively. To penicillin, 71% of S. pneumoniae were nonsusceptible. Resistance rates of E. coli were 11% to cefotaxime, 8% to cefoxitin, and 34% to fluoroquinolone, and those of K. pneumoniae were 22% to ceftazidime, and 16% to cefoxitin. Lowest resistance rates to cephalosporins shown by E. cloacae and S. marcescens were to cefepime, 7% and 17%, respectively. This is the first KONSAR surveillance, which detected imipenem-resistant E. coli and K. pneumoniae. To imipenem, 22% of P. aeruginosa and 9% of Acinetobacter spp. were resistant. Trends of resistances showed a slight reduction in MRSA and in penicillin-nonsusceptible S. pneumoniae, but an increase in ampicillin-resistant E. faecium. Ampicillin-resistant E. coli and H. influenzae remained prevalent. Compared to the previous study, amikacin- and fluoroquinolone- resistant Acinetobacter spp. increased to 60% and 62%, respectively. Ceftazidime-resistant K. pneumoniae decreased slightly, and imipenem-resistant P. aeruginosa and Acinetobacter spp., and vancomycin-resistant E. faecium increased. In conclusion, vancomycin-resistant E. faecium, cefoxitin-resistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa and Acinetobacter spp. increased gradually, and imipenem-resistant E. coli and K. pneumoniae appeared for the first time. Continued surveillance is required to prevent further spread of these serious resistances.

AB - Continued antimicrobial resistance surveillance can provide valuable information for the empirical selection of antimicrobial agents for patient treatment, and for resistance control. In this 6th annual study for 2002, the susceptibility data at 39 Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) hospitals were analyzed. Resistance rates of S. aureus were 67% to oxacillin, and 58% to clindamycin. The ampicillin and vancomycin resistance rates of E. faecium were 89% and 16%, respectively. To penicillin, 71% of S. pneumoniae were nonsusceptible. Resistance rates of E. coli were 11% to cefotaxime, 8% to cefoxitin, and 34% to fluoroquinolone, and those of K. pneumoniae were 22% to ceftazidime, and 16% to cefoxitin. Lowest resistance rates to cephalosporins shown by E. cloacae and S. marcescens were to cefepime, 7% and 17%, respectively. This is the first KONSAR surveillance, which detected imipenem-resistant E. coli and K. pneumoniae. To imipenem, 22% of P. aeruginosa and 9% of Acinetobacter spp. were resistant. Trends of resistances showed a slight reduction in MRSA and in penicillin-nonsusceptible S. pneumoniae, but an increase in ampicillin-resistant E. faecium. Ampicillin-resistant E. coli and H. influenzae remained prevalent. Compared to the previous study, amikacin- and fluoroquinolone- resistant Acinetobacter spp. increased to 60% and 62%, respectively. Ceftazidime-resistant K. pneumoniae decreased slightly, and imipenem-resistant P. aeruginosa and Acinetobacter spp., and vancomycin-resistant E. faecium increased. In conclusion, vancomycin-resistant E. faecium, cefoxitin-resistant E. coli and K. pneumoniae, and imipenem-resistant P. aeruginosa and Acinetobacter spp. increased gradually, and imipenem-resistant E. coli and K. pneumoniae appeared for the first time. Continued surveillance is required to prevent further spread of these serious resistances.

KW - Antimicrobial resistance

KW - Imipenem resistance

KW - Korean resistance surveillance

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U2 - 10.3349/ymj.2004.45.4.598

DO - 10.3349/ymj.2004.45.4.598

M3 - Article

C2 - 15344199

AN - SCOPUS:4644320433

SN - 0513-5796

VL - 45

SP - 598

EP - 608

JO - Yonsei Medical Journal

JF - Yonsei Medical Journal

IS - 4

ER -

Increasing prevalence of vancomycin-resistant enterococci, and cefoxitin-, imipenem- and fluoroquinolone-resistant gram-negative bacilli: A KONSAR Study in 2002

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Keywords

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