Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study

Y. S. Kim; D. S. Han; Y. H. Kim; W. H. Kim; J. S. Kim; H. S. Kim; H. S. Kim; Y. S. Park; H. J. Song; S. J. Shin; S. K. Yang; B. D. Ye; C. S. Eun; K. M. Lee; S. H. Lee; B. I. Jang; S. A. Jung; J. H. Cheon; C. H. Choi; K. C. Huh

doi:10.1017/S0950268812000581

Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study

Y. S. Kim, D. S. Han, Y. H. Kim, W. H. Kim, J. S. Kim, H. S. Kim, H. S. Kim, Y. S. Park, H. J. Song, S. J. Shin, S. K. Yang, B. D. Ye, C. S. Eun, K. M. Lee, S. H. Lee, B. I. Jang, S. A. Jung, J. H. Cheon, C. H. Choi, K. C. Huh

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

SUMMARY The incidence and severity of Clostridium difficile infections (CDI) have increased in Western countries. However, there are limited data regarding the epidemiology of CDI in Eastern countries. This nationwide study was conducted in 17 hospitals to determine temporal trends in CDI incidence (from 2004 to 2008) in South Korea. The total incidence of CDI in Korea was 1·7 cases/1000 adult admissions in 2004, and 2·7/1000 cases in 2008 (P' =' 0·028). When analysing the clinical features of 1367 CDI patients diagnosed in 2008, oral metronidazole was effective as a first-line treatment for CDI (61·9%). Relapse rate was 8·9% and complicated CDI was only observed in 3·6%. The incidence of CDI increased significantly in Korea from 2004 to 2008. Although the clinical features were milder than in Western countries, the increasing burden of CDI needs ongoing surveillance systems.

Original language	English
Pages (from-to)	189-194
Number of pages	6
Journal	Epidemiology and Infection
Volume	141
Issue number	1
DOIs	https://doi.org/10.1017/S0950268812000581
State	Published - Jan 2013

Keywords

Clostridium difficile infection
Korea
incidence

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Kim, Y. S., Han, D. S., Kim, Y. H., Kim, W. H., Kim, J. S., Kim, H. S., Kim, H. S., Park, Y. S., Song, H. J., Shin, S. J., Yang, S. K., Ye, B. D., Eun, C. S., Lee, K. M., Lee, S. H., Jang, B. I., Jung, S. A., Cheon, J. H., Choi, C. H., & Huh, K. C. (2013). Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study. Epidemiology and Infection, 141(1), 189-194. https://doi.org/10.1017/S0950268812000581

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title = "Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study",

abstract = "SUMMARY The incidence and severity of Clostridium difficile infections (CDI) have increased in Western countries. However, there are limited data regarding the epidemiology of CDI in Eastern countries. This nationwide study was conducted in 17 hospitals to determine temporal trends in CDI incidence (from 2004 to 2008) in South Korea. The total incidence of CDI in Korea was 1·7 cases/1000 adult admissions in 2004, and 2·7/1000 cases in 2008 (P' =' 0·028). When analysing the clinical features of 1367 CDI patients diagnosed in 2008, oral metronidazole was effective as a first-line treatment for CDI (61·9%). Relapse rate was 8·9% and complicated CDI was only observed in 3·6%. The incidence of CDI increased significantly in Korea from 2004 to 2008. Although the clinical features were milder than in Western countries, the increasing burden of CDI needs ongoing surveillance systems.",

keywords = "Clostridium difficile infection, Korea, incidence",

author = "Kim, {Y. S.} and Han, {D. S.} and Kim, {Y. H.} and Kim, {W. H.} and Kim, {J. S.} and Kim, {H. S.} and Kim, {H. S.} and Park, {Y. S.} and Song, {H. J.} and Shin, {S. J.} and Yang, {S. K.} and Ye, {B. D.} and Eun, {C. S.} and Lee, {K. M.} and Lee, {S. H.} and Jang, {B. I.} and Jung, {S. A.} and Cheon, {J. H.} and Choi, {C. H.} and Huh, {K. C.}",

year = "2013",

month = jan,

doi = "10.1017/S0950268812000581",

language = "English",

volume = "141",

pages = "189--194",

journal = "Epidemiology and Infection",

issn = "0950-2688",

publisher = "Cambridge University Press",

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Kim, YS, Han, DS, Kim, YH, Kim, WH, Kim, JS, Kim, HS, Kim, HS, Park, YS, Song, HJ, Shin, SJ, Yang, SK, Ye, BD, Eun, CS, Lee, KM, Lee, SH, Jang, BI, Jung, SA, Cheon, JH, Choi, CH & Huh, KC 2013, 'Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study', Epidemiology and Infection, vol. 141, no. 1, pp. 189-194. https://doi.org/10.1017/S0950268812000581

TY - JOUR

T1 - Incidence and clinical features of Clostridium difficile infection in Korea

T2 - A nationwide study

AU - Kim, Y. S.

AU - Han, D. S.

AU - Kim, Y. H.

AU - Kim, W. H.

AU - Kim, J. S.

AU - Kim, H. S.

AU - Park, Y. S.

AU - Song, H. J.

AU - Shin, S. J.

AU - Yang, S. K.

AU - Ye, B. D.

AU - Eun, C. S.

AU - Lee, K. M.

AU - Lee, S. H.

AU - Jang, B. I.

AU - Jung, S. A.

AU - Cheon, J. H.

AU - Choi, C. H.

AU - Huh, K. C.

PY - 2013/1

Y1 - 2013/1

N2 - SUMMARY The incidence and severity of Clostridium difficile infections (CDI) have increased in Western countries. However, there are limited data regarding the epidemiology of CDI in Eastern countries. This nationwide study was conducted in 17 hospitals to determine temporal trends in CDI incidence (from 2004 to 2008) in South Korea. The total incidence of CDI in Korea was 1·7 cases/1000 adult admissions in 2004, and 2·7/1000 cases in 2008 (P' =' 0·028). When analysing the clinical features of 1367 CDI patients diagnosed in 2008, oral metronidazole was effective as a first-line treatment for CDI (61·9%). Relapse rate was 8·9% and complicated CDI was only observed in 3·6%. The incidence of CDI increased significantly in Korea from 2004 to 2008. Although the clinical features were milder than in Western countries, the increasing burden of CDI needs ongoing surveillance systems.

AB - SUMMARY The incidence and severity of Clostridium difficile infections (CDI) have increased in Western countries. However, there are limited data regarding the epidemiology of CDI in Eastern countries. This nationwide study was conducted in 17 hospitals to determine temporal trends in CDI incidence (from 2004 to 2008) in South Korea. The total incidence of CDI in Korea was 1·7 cases/1000 adult admissions in 2004, and 2·7/1000 cases in 2008 (P' =' 0·028). When analysing the clinical features of 1367 CDI patients diagnosed in 2008, oral metronidazole was effective as a first-line treatment for CDI (61·9%). Relapse rate was 8·9% and complicated CDI was only observed in 3·6%. The incidence of CDI increased significantly in Korea from 2004 to 2008. Although the clinical features were milder than in Western countries, the increasing burden of CDI needs ongoing surveillance systems.

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EP - 194

JO - Epidemiology and Infection

JF - Epidemiology and Infection

IS - 1

ER -

Incidence and clinical features of Clostridium difficile infection in Korea: A nationwide study

Abstract

Keywords

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